The CDC presented considerations for distinguishing influenza-like illness from inhalational anthrax (MMWR, 9 Nov 01, 50:44 pp. 984-986). “Although many different illness might present with influenza-like illnesses (ILI) symptoms, the presence of certain signs and symptoms might help to distinguish other causes of ILI from inhalational anthrax. Nasal congestion and rhinorrhea are features of mo...

This article summarizes the development of cellular neuropharmacology and neurotoxicology, based primarily on my own research. The progress of this field depends at least in part on the theoretical and technological developments of excitable cell physiology, biophysics, and biochemistry. First, a brief historical development is described. Second, my earlier studies of the mechanism of action of...

Anthrax is a highly contagious and potentially fatal human disease caused by Bacillus anthracis, an aerobic, Gram-positive, spore-forming rod-shaped bacterium with worldwide distribution as a zoonotic infection in herbivore animals. Bioterrorist attacks with inhalational anthrax have prompted the development of more effective treatments. Antibodies against anthrax toxin have been shown to decre...

BACKGROUND Asthma is a chronic inflammatory condition of the airways that affects roughly 358 million people globally. It is a serious global health problem with an increasing prevalence worldwide. Most people affected are in low- and middle-income countries including Ethiopia. The association between non -adherence and poor disease control is clearly stated in different literatures. The main o...

Since 1957, it has been proposed that the dissemination of inhalational anthrax required spores to be transported from the lumena of the lungs into the lymphatic system. In 2002, this idea was expanded to state that alveolar macrophages act as a "Trojan horse" capable of transporting spores across the lung epithelium into draining mediastinal lymph nodes. Since then, the Trojan horse model of d...

A previously healthy 26-year-old woman developed hemorrhagic alveolitis and adult respiratory distress syndrome (ARDS) following use of a hydrofluoric acid-containing household cleaning agent. Exposure was inhalational in nature. The circumstances and possible mechanism of chemical pneumonitis from low-dose inhalational exposure to hydrofluoric acid are discussed.

Outpatients expect to be able to walk into hospital and out again. They are usually unsedated and often apprehensive. When they are anaesthetized, induction must be rapid, depth of anaesthesia must be deep enough for the operative procedures performed—yet not so deep as to obtund protective reflexes—and prolonged recovery must be avoided. Many anaesthetic techniques are used with the aim of pro...

toxic reactions to local anesthetics may occur due to over dose, accidental intravenous injections or rapid systemic uptake of the drugs. but there have been few reports on toxicity due to displacement of epidural catheters after an initial correct insertion and performance of a test dose.  here we present a case of local anesthetics toxicity due to possible displacement of the epidural cathete...