نتایج جستجو برای: inhibition assay

تعداد نتایج: 525299  

Journal: :The Journal of biological chemistry 1966
P W Camerino T E King

The extent of inhibition of cytochrome oxidase activity by cyanide depends upon the method of assay. It has been contimed that this inhibition is “readily reversible” with the use of the standard manometric technique. However, in the spectrophotometric assay only about 10% of the control activity is observed after the cyanide is removed by physical methods. The polarographic assay yields interm...

Journal: :Antimicrobial agents and chemotherapy 1993
M J Otto C D Reid S Garber P Y Lam H Scarnati L T Bacheler M M Rayner D L Winslow

XM323 represents a novel class of potent inhibitors of human immunodeficiency virus (HIV) protease. In vitro studies have shown that inhibition of this enzyme translates into potent inhibition of replication of HIV type 1 (HIV-1) and HIV-2. The inhibition of virus replication was assessed with three assays designed to measure the production of infectious virus, viral RNA, or p24 antigen. The pr...

2005
RANDOLPH T. WEDDING

Phosphoenolpyruvate carboxylase partially purified from leaves of Crassula and rendered insensitive to malate by storage without adjuvants can be altered to the form sensitive to malate inhibition by brief, 5-minute preincubation with 5 millimolar malate. The induction of malate sensitivity is reversible by lowering the malate2concentration. Of the reaction components only HC03increases the sen...

Journal: :Cancer research 1985
M Hirota K Fukushima P I Terasaki G Y Terashita M Kawahara D Chia N Suyama H Togashi

A new cell-binding inhibition assay to detect tumor-associated antigens in sera was developed. This assay determined that sialosylated Lewisx, as detected by the CSLEX1 monoclonal antibody, is present in the sera of 95% of patients with advanced lung adenocarcinomas. Sera with inhibition titers of 1:16 or higher were presumed to contain sialosylated Lewisx. Tests of over 900 sera samples from b...

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