in an endeavor to find a novel series of antihyperglycemic agents, new benzimidazole and pyrimidine derivatives were successfully synthesized efficiently in high yield with high purity, starting from amino acids in the presence of phosphorus oxychloride (pocl3). the synthesized compounds were identified by 1h-nmr, 13c-nmr, ft-ir spectroscopic techniques and elemental analysis. all products were...

executive dysfunction theory in autism spectrum disorders is basis for many features of this disorders in social and non social areas. the purpose of research was study of response inhibition in children with autism spectrum disorders using computerized stroop test. this study was causal-comparative research. convenient sampling method were used for selected of 15 boy with autism spectrum disor...

objectives: the purpose of this study was to compare the relationship between theory of mind and inhibitory responses in normal children and adhd. methods: this study is descriptive study, a sample size of 25 patients adhd children and 30 normal children, who were randomly selected. research instruments are questionnaires theory of mind and computerized stroop test. results: the results showed ...

this work studies the biosurfactants production which enables the diesel biodegradation byusing mixed microbial consortia from polluted sites. it was carried out by culturing three microbial consortia(named as xa, xb and xc) obtained from polluted soils, and enriched in diesel as sole carbon source.batchexperiments were done to study the effects of three variables (temperature,hydrocarbon conce...

to prepare hemagglutination inhibition (hi) antigen the egg drop syndrome virus (edsv) was propagated in 10-day-old embryonated duck eggs. the virus antigen was inactivated with two methods including heating (65°c) and adding 0.5% formaldehyde by considering low destroying effect on hemagglutination (ha) and hi titers. the edsv hi titers of 310 sera and 100 yolks obtained from 23 chicken farms ...

In silico Optimization of a FragmentBased Hit Yields Biologically Active, High-Efficiency Inhibitors for Glutamate Racemase FERM conclusions: A novel lead compound for inhibition of the antibacterial drug target, glutamate racemase, was optimized for both potency and lipophilic efficiency. A hybrid MD–docking and scoring scheme, FERM-SMD, was used to predict the relative potencies of potential ...

This research is the first to evaluate brittle wort (Chara corallina) extract for phytochemical content and inhibitory effects against a-glucosidase a-amylase activities. An ethanolic of C. corallina had strongest enzyme effect. The inhibition efficiencies all extracts were more potent than those a-glucosidase, with IC50 values 8.43±0.18 mg/mL 1.78±0.07 a-amylase. Inhibition efficiency was rela...

Traditional assays that monitor cAMP inhibition by opioid receptor ligands require second-messenger accumulation over periods of 10–20 minutes. Since receptor regulation occurs within a similar time frame, such assays do not discriminate the actual signal from its modulation. Here we used bioluminescence resonance energy transfer to monitor inhibition of cAMP production by d-opioid receptor (DO...

Traditional assays that monitor cAMP inhibition by opioid receptor ligands require second-messenger accumulation over periods of 10-20 minutes. Since receptor regulation occurs within a similar time frame, such assays do not discriminate the actual signal from its modulation. Here we used bioluminescence resonance energy transfer to monitor inhibition of cAMP production by δ-opioid receptor (DO...

In this article, the corrosion inhibition of steel DIN 2391 St 37-4 in acidic medium 5% H2SO4 with and without presence eco inhibitors leaf (Petroselinum Sativum) was examined. Inhibitory properties parsley leaves on were examined by potentiodynamic polarization - Tafel extrapolation, FTIR method order to categorize oxide layer. The test performed static stirring at 600 rpm. By extrapolation ba...