STUDY DESIGN Retrospective study. PURPOSE To compare the neurological outcome of transforaminal debridement and interbody fusion with transpedicular decompression for treatment of thoracic and lumbar spinal tuberculosis. OVERVIEW OF LITERATURE Few articles have addressed the impact of neurological recovery in patients with tuberculosis who were treated by two different operative methods via...

OBJECTIVE To evaluate the clinical effect of the minimally invasive transforaminal lumbar interbody fusion combined with posterolateral fusion and unilateral fixation using a tubular retractor in the management of degenerative lumbar disease. METHODS A retrospective analysis was conducted to analyze the clinical outcome of 58 degenerative lumbar disease patients who were treated with minimall...

STUDY DESIGN Controlled laboratory study. OBJECTIVE To evaluate the biomechanical characteristics of a new expandable interbody cage in single-segment posterior lumbar interbody fusion (PLIF) using cadaveric lumbar spines. SUMMARY OF BACKGROUND DATA One of the popular methods of treating lumbar spine pathologies involves a posterior lumbar interbody fusion using bilateral interbody nonexpan...

We carried out a prospective study to determine whether the addition of a recombinant human bone morphogenetic protein (rhBMP-2) to a machined allograft spacer would improve the rate of intervertebral body fusion in the spine. We studied 77 patients who were to undergo an interbody fusion with allograft and instrumentation. The first 36 patients received allograft with adjuvant rhBMP-2 (allogra...

STUDY DESIGN A questionnaire survey. OBJECTIVE To report the current use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in lumbar fusion procedures for the treatment of degenerative spondylolisthesis (DS), and identify associated factors including fusion technique, surgeon location, surgeon specialty, or surgeon practice model. SUMMARY OF BACKGROUND DATA The prevalence of rhBMP...

BACKGROUND Since the introduction of rhBMP-2 (Infuse) in 2002, surgeons have had an alternative substitute to autograft and its related donor site morbidity. Recently, the prevalence of reported adverse events and complications related to the use of rhBMP-2 has raised many ethical and legal concerns for surgeons. Additionally, the cost and decreasing reimbursement landscape of rhBMP-2 use have ...

Lumbar degenerative disease is the major cause of low back pain. Currently, surgical treatment remains the standard care for lumbar degenerative disease. This study aimed to evaluate the efficacy and complications of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) for the treatment of single-segment lumbar degenerative disease. A total of 75 patients with single-segment lum...