background: approximately 10-14% of the clinically acknowledged pregnancies end with spontaneous abortion at caucasian population. possible immunologic causes of recurrent miscarriages have been extensively researched. the change in the cytokines balance synthesis in favor of those synthesized by th2 cells with an increase of interleukin 6 (il6) and interleukin10 (il10) secretion is considered ...

T cell with chimeric antigen receptors (CAR-T) has presented remarkable efficacy for blood cancer as an emerging immunotherapy. However, solid tumors, the therapeutic is much impaired due to lack of infiltration and persistence CAR-T in tumor tissue. Thus, we constructed interleukin-7-loaded oncolytic adenovirus combined use virus improve outcome. We (oAD-IL7) a B7H3-targeted explored single oA...