Specific delivery of therapeutic agents to solid tumors and their bioavailability at the target site are the most clinically important and challenging goals in cancer therapy. Liposomes are promising nanocarriers and have been well investigated for cancer therapy. In spite of preferred accumulation in tumors via the enhanced permeability and retention (EPR) effect, inefficient drug release at t...

Thank you very much for publishing our manuscript entitled: "Quantification and comparison of bone-specific alkaline phosphatase with two methods in normal and paget's specimens" in the latest issue of the journal (Caspian Journal of Internal Medicine, Summer 2012 3(3):478-483). Unfortunately, we noticed the mistake in the date of our study after its publication in your latest revised manuscrip...

The major reason for the prediction of thermodynamic properties of mercury lies in the fact that itsintermolecular interactions highly depend on temperature and density. Internal pressure is a good criterion toinvestigate the density dependence of the interatomic interactions. Because its physical base is a forcetending to close together the molecules that is intermolecular interactions, and as...

Specific delivery of therapeutic agents to solid tumors and their bioavailability at the target site are the most clinically important and challenging goals in cancer therapy. Liposomes are promising nanocarriers and have been well investigated for cancer therapy. In spite of preferred accumulation in tumors via the enhanced permeability and retention (EPR) effect, inefficient drug release at t...

We describe an approach to robot introspection based on self observation and communication. Self observation is what the robot should do in order to build, represent and understand its internal state. It is necessary to translate the state representation in order to build a suitable input to an ontology that supplies the meaning of the internal state. The ontology supports ...

L. A. Citro, S. E. Sansom, M. Khan, M. M. Martin, P. Kuppusamy, and T. S. Elton. 2,4 Internal Medicine, The Ohio State University, Columbus, Ohio, United States, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio, United States, Internal Medicine, Division of Cardiovascular Medicine, The Ohio State University, Columbus, Ohio, United States, College of Medicine, D...

Fluctuations of membrane potential of cortical neurons, referred to here as internal states, are essential for brain function, but little is known about how these internal states emerge and are maintained, or what determines transitions between these states. We performed intracellular recordings from hippocampal CA3 pyramidal cells ex vivo and found that neurons display multiple and hierarchica...

This article deals with the determination of temperature distribution, displacement and thermal stresses of a rectangular plate having nonhomogeneous material properties with internal heat generation. The plate is subjected to sectional heating. All the material properties except Poisson’s ratio and density are assumed to be given by a simple power law along x direction. Solution of the two-dim...

Photodissociation dynamics for various tryptophan chromophores was studied at 193 or 248 nm using multimass ion imaging techniques. The competition between internal conversion to the ground electronic state and dissociation from the repulsive excited state reveals size-dependent photostability for these amino acid chromophores. As the size of chromophore increases, internal conversion to the gr...

are copies of a single synchronous finite-state machine M. The internal state of a cell at time t @ 1 depends on its internal state and on the internal states of its left and right neighbors at time t. At time t 0, one of the end cells (called "the general") enters an internal state s, ("fire when ready"), while all other cells (called "the soldiers") are in a quiescent state sq. The array must...