The links of minority stressors (workplace discrimination, expectations of stigma, internalized heterosexism, and identity management strategies) with psychological distress and job satisfaction were examined in a sample of 326 sexual minority employees. Drawing from minority stress theory and the literature on the vocational experiences of sexual minority people, patterns of mediation and mode...

GLUT4 constitutively recycles between the plasma membrane and intracellular depots. Insulin shifts this dynamic equilibrium towards the plasma membrane by recruiting GLUT4 to the plasma membrane from insulin-responsive vesicles. Muscle is the primary site for dietary glucose deposition; however, how GLUT4 sorts into insulin-responsive vesicles, and if and how insulin resistance affects this pro...

purpose: a large number of people with attention deficit/hyperactivity disorder in adolescence, in addition to problems related toattention deficit/hyperactivityalso suffer from internalizing problems comorbid anxiety and depression. this research aim to investigate the effect of mindfulness based treatment on improvement of internalized problems of adolescent suffering from adhd. method: the p...

Little is known about internalized stigma of mental illness in India. A reason for this could be the lack of valid assessment instruments adapted for the diverse cultures and languages of the country. One of the most widely used and accepted questionnaires to assess internalized stigma is the 29-item Internalized Stigma of Mental Illness (ISMI) scale. The aim of the present study was to transla...

We studied the endocytosis of fluorescent glycosphingolipid (GSL) analogs in various cell types using pathway-specific inhibitors and colocalization studies with endocytic markers and DsRed caveolin-1 (cav-1). Based on inhibitor studies, all GSLs tested were internalized predominantly (>80%) by a clathrin-independent, caveolar-related mechanism, regardless of cell type. In addition, fluorescent...

Previously, modified LDLs were shown to stimulate macropinocytosis in pigeon macrophages. Simultaneous intracellular trafficking of LDL and AcLDL, differentially labeled with colloidal gold, was done to determine whether uptake of LDL, which does not cause foam cell formation, was internalized via a separate route from AcLDL, which stimulates foam cell formation. AcLDL and LDL were followed at ...

We investigated the relationship between internalized stigma of mental illness at baseline and depressive and psychotic symptoms 3 and 6 months later, controlling for baseline symptoms. Data on homeless veterans with severe mental illness (SMI) were provided by the Northeast Program Evaluation Center (NEPEC) Special Needs-Chronic Mental Illness (SN-CMI) study (Kasprow and Rosenheck, 2008). The ...

CONSTRUCT VALIDATION OF THE INTERNALIZED RACIAL OPPRESSION SCALE by Tamba-Kuii M. Bailey Racism has been identified as a profoundly traumatic and a psychologically damaging experience affecting Black people (Harrell, 2000; White & Parham, 1990; Williams & Williams-Morris, 2000). It has been theorized that one of the most devastating effects racial oppression (i.e. racism and discrimination) is ...

Background: Stigma is the most chal‌lenging care responsibility in families of individuals with psychological disorders. Considering the evident impacts of cultural and social circumstances on stigma, less attention has been paid to this issue and the conducted interventions are limited. Aim: todetermine the effects of psychoeducation on stigma in family caregivers of patients with schizophreni...

The present study was performed to identify sequence(s) in the third intracellular loop (i3) of the muscarinic acetylcholine receptor M4 subtype (M4 receptor) involved in its internalization and recycling. In transiently transfected human embryonic kidney 293-tsA201 cells, 40 to 50% of cell-surface M4 receptors are internalized in an agonist-dependent manner, and approximately 65% of internaliz...