We have previously demonstrated that interleukin-4 (IL-4) induces tyrosine phosphorylation of a protein closely related or identical to the c-fes proto-oncogene product (FES) and association of this protein with the IL-4 receptor alpha chain (IL-4R alpha). IL-4 is known to induce association of phosphatidylinositol-3 (PI3) kinase with the IL-4R alpha. Since FES contains the consensus motifs for...

Functional electrical stimulation (FES) has been studied and clinically applied to restoring or assisting motor functions lost due to spinal cord injury or cerebrovascular disease. Electrical stimulation without control of functional movements is also used for therapy or in rehabilitation training. In recent years, one of the main focuses of FES studies has been its application for rehabilitati...

Estrogen receptor (ER) expression in breast cancer is associated with a more favorable prognosis and is necessary for a response to endocrine therapies. Traditionally, ER expression is assessed by in vitro assays on biopsied tumor tissue. However, recent advances have allowed in vivo evaluation of ER expression with (18)F-fluoroestradiol ((18)F-FES) PET. Clinical studies have demonstrated the u...

We present a Hubbard-corrected density functional theory investigation of FeS polymorphs based on the quasi-harmonic theory of lattice vibrations. We show that the first temperature transition of troilite FeS cannot involve the MnP-type FeS phase, as sometimes reported in the literature, while the sequence of polymorphs in the pressure range 0–100 GPa at room temperature supports the experiment...

This study aims to investigate the clinical efficacy of Dextran 40 plus dexamethasone on the prevention of fat embolism syndrome (FES) in high-risk patients with long bone shaft fractures. According to the different preventive medication, a total of 1837 cases of long bone shaft fracture patients with injury severity score (ISS) > 16 were divided into four groups: dextran plus dexamethasone gro...

This paper presents the technological advancements in neural prosthesis devices using Functional Electrical Stimulation (FES). FES refers to the restoration of motor functions lost due to spinal cord injury (SCI), stroke, head injury, or diseases such as Cerebral Palsy or Multiple Sclerosis by eliciting muscular contractions through the use of a neuromuscular electrical stimulator device. The f...

Animal word list generation (ANWLG) was administered to 47 first-episode schizophrenia (FES) participants and 31 controls. Fifty-nine left temporal lobe epilepsy (LTLE) participants were included as a comparison group with known temporal lobe damage and expected semantic deficits. Semantic knowledge was assessed with the Association Index (AI), a measure of the semantic relatedness of all conse...

Functional electrical stimulation (FES) may be able to augment functional arm and hand movement after stroke. Poststroke neuroprostheses that incorporate voluntary effort and FES to produce the desired movement must consider how forces generated by voluntary effort and FES combine, even in the same muscle, in order to provide an appropriate level of stimulation to elicit the desired assistive f...

This presentation will review briefly the current practice and state of the art in functional electrical stimulation (FES) as applied to stroke, head injured or brain tumour operated patients. A similar application is used in paretic patients following trauma or other aetiology. Over 20 years experience in the application of FES, as practised in Ljubljana, will be highlighted and the devices cu...

Abstract The effects of long-term Functional Electrical Stimulation (FES) assisted walking on ankle dynamic stiffness were examined in spinal cord injured (SCI) subjects with incomplete motor function loss. A parallelcascade system identification method was used to identify intrinsic and reflex contributions to dynamic ankle stiffness at different positions with subjects instructed to remain re...