OBJECTIVE To establish a rodent model for skin grafting with fibrin glue and examine the effects of fibrin glue on the adhesive strength of skin grafts without bolsters. STUDY DESIGN Animal cohort. SETTING Academic hospital laboratory. SUBJECTS AND METHODS Three skin grafts were created using a pneumatic microtome on the dorsum of 12 rats. Rats were evenly divided into experimental (n = 6...

Human skin grafted upon the chorio-allantoic membrane of chick embryos adheres and becomes nourished for as long as 10 days. Occasionally regrafts upon a second egg have succeeded and thus prolonged the vitality of the graft to 14 days. In successful experiments the epithelium of the chorio-allantois fuses with that of the graft, the collagen fibers of the corium interlace with those of the mem...

This is a report on the technique of neoglans reconstruction in a patient with amputated glans penis following guillotine neonatal circumcision. A 4 cm long and 2 cm wide lower lip oral mucosa graft was harvested and used to graft the distal 2 cm of the corporal bodies after 2 cm of the distal penile skin had been excised. One edge of the lower lip oral mucosa graft was anastomosed to the ureth...

a 14 year old boy suffering from marked penoscrotal lymphedema is reported. reduction scrotoplasty was done and the neoscrotum was made by combining the anterior suprapubic and posterior scrotal v-shaped flaps. a split-thickness skin graft from the thigh was placed over the denuded penis. no complication was encountered and the cosmetic result was satisfactory

The use of an osteocutaneous free fibular graft as a single-stage reconstructive procedure for composite tissue loss is increasingly common. Detailed anatomical study in cadavers of the blood supply to the graft demonstrates cutaneous arteries arising from the peroneal artery and then passing along the posterior surface of the lateral intermuscular septum. These vessels pierce the crural fascia...

burns account for a significant proportion of injuries, and of these the face, neck, and anterior torso are commonly affected. burn scars remain a lasting reminder of the insult both for the patient and the outside world. there is little doubt that the change in appearance and the limitation imposed by a burn scar contribute to negative body image. treatment of hypertrophic scars in the neck ha...

OBJECTIVES FTY720 modulates CD4+T cells by the augmentation of regulatory T cell activity, secretion of suppressive cytokines and suppression of IL-17 secretion by Th17 cells. To further understand the process of graft rejection/acceptance, we evaluated skin allograft survival and associated events after FTY720 treatment. METHODS F1 mice (C57BL/6xBALB/c) and C57BL/6 mice were used as donors f...

BACKGROUND Surgical treatment of skin melanoma with skin margins in accordance with tumor thickness often necessitates covering the surgical defect with full or partial thickness skin grafts. When selective sentinel node biopsy is indicated, traditional procedures require 3 incisions: 1 in the region of the primary tumor covered by the graft, 1 in the axilla or groin corresponding to the site o...

thickness skin graft to a large surgical wound in a patient with sclerodermatous skin. In this case history, the key point is a clinical one—that wound healing may be uncomplicated even if the graft is taken from affected sclerodermatous skin and transplanted to another affected area. There are reports in the literature of using artificial [8], split thickness [9] and autologous [10] skin graft...

Objective: To explore the methods for the repair of large-area limb skin avulsion wound. Method: Eleven patients with simple limb skin avulsion underwent large-area stereotypy full-thickness skin graft for wound repair. Results: Wounds were repaired very well as well as the late appearance and functions were satisfactory in all 11 patients. During follow-up, the hypertrophic scars were mild, th...