BACKGROUND Intracranial aneurysms are abnormal dilations of the cerebral arteries of unknown origin. However, some genes have been linked to their formation, as in the case of NOS3 gene which encodes the endothelial nitric oxide synthase responsible for producing nitric oxide. Several polymorphisms in this gene, in association with a variable number tandem repeat located in intron 4 from eNOS4 ...

Background: Intracranial aneurysm is a common cerebrovascular disease, which cause wide concern by neurosurgeons. The 3D–DSA images simulated surgical path may improve the success rate of operation in bridging surgery of emergency ruptured intracranial aneurysms. Methods: Eighteen patients with intracranial ruptured aneurysms that underwent craniotomy clipping surgery from January 2015 to Janua...

BACKGROUND AND PURPOSE The natural history of cerebral aneurysms is thought to be governed by multifactorial processes involving hemodynamics, biomechanics, mechanobiology, and perianeurysmal environment. The purpose of this study was to highlight the importance of considering the influence of contacts with perianeurysmal environment structures on the hemodynamics and geometric evolution of int...

PURPOSE To explain the origin and growth of intracranial aneurysms using the hemodynamic data obtained from a computer simulation. MATERIALS AND METHODS Pulsatile flow in an intracranial aneurysm cavity was numerically simulated based on physiologic pulsatile flow observed in the aorta. A finite element method was applied to solve the equations of motion and the non-Newtonian viscosity of blo...

Giant vertebral and vertebrobasilar (VB) aneurysms constitute a rare form of intracranial aneurysms that exhibit a dismal natural history associated with significant morbidity and mortality.1 Current endovascular treatments include coil embolization as well as the more recent use of flow-diverting stents, each having known risks of aneurysm recurrence, ischemia, and death.2 Extracranial–intracr...

Traumatic intracranial aneurysms are rare and account for less than 1% of cerebral aneurysms in the adult population. Despite their low incidence, the risk of delayed rupture with intracranial hemorrhage is high and mandates treatment. Surgical treatments with aneurysm clipping or parent vessel sacrifice have disadvantages given patient comorbidities after head trauma. Endovascular coiling offe...

An 85-year-old man complained of a 2-month history of pain on the left side of his face. Brain computed tomography (CT) and magnetic resonance imaging/magnetic resonance angiography did not clearly show any intracranial abnormality and only showed fluid effusion in his left sphenoid sinus. Filamentous fungi were detected from the left sphenoid sinus specimen. The isolate was Scedosporium apiosp...

BACKGROUND Accessing the normal distal vessel in treatment of wide-necked giant intracranial aneurysms with flow diversion can be difficult. CASE DESCRIPTION Through illustrative cases, the authors present several useful techniques in distal access of wide-necked giant aneurysms during flow diversion treatment. Obtaining an optimal projection that separates the outflow limb from the aneurysm ...

Abstract Introduction The current paper presents an examination of the emerging role deep learning-based simulation software in enhancing preprocedural planning for intracranial aneurysm treatment using flow diverters. Intracranial aneurysms pose significant risk due to their potential rupture leading life-threatening subarachnoid hemorrhage. Innovative endovascular options like diverters, whic...