Objective: Magnesium sulfate has been shown to provide analgesia when administered into the knee joints. The aim of this study was to evaluate the histopathological effects of intraarticular administration of magnesium sulfate in the rat knee joint. Design: A total of 50 rats were given 0.25ml of magnesium sulfate (10%) by injection into the right knee joint and 0.25ml of 0.9% saline solution b...

Magnesium sulfate has been used in preeclampsia patients in order to prevent seizure. It is also used for the treatment of arrhythmia and asthma and as an anesthetic adjunct in patients undergoing surgery for pheochromocytoma. However, its potentiating effects on perioperative analgesia and muscle relaxation have drawn attention recently. These characteristics of magnesium (anesthetic- and anal...

OBJECTIVE To review the function and use of intravenous magnesium in magnesium depleted and non-magnesium depleted patients. DATA SOURCES A review of studies reported from 1966 to 1998 and identified through a MEDLINE search of the English-language literature on the use of intravenous magnesium. SUMMARY OF REVIEW Magnesium is a metalo-coenzyme that participates in numerous enzymatic reactio...

BACKGROUND Our study analyzes the effect of magnesium supplementation on nephrotoxicity in patients receiving cisplatin for head and neck cancer. METHODS We retrospectively reviewed the medical records of patients with head and neck cancer who received two doses of cisplatin (80 mg/m2) and 5-fluorouracil (800 mg/m2) 3 weeks apart from August 2008 to October 2012. The regimen prior to 2011 (cr...

alkali and alkaline earth metals hydrogen sulfate catalyzed the one-pot three component condensation reactions of aldehydes, 1,3-dicarbonyl compounds and urea or thiourea under solvent-free conditions leading to 3,4-dihydropyrimidin-2(1h)-ones in high yields at 80 °c. our results showed that biginelli reaction not only is ph dependent, but the cation of catalyst plays an important role.

The effect of the parenteral administration of magnesium sulfate on the renal hemodynamics of normal dogs (1) and normal children (2) has been previously reported. However, no data are available concerning the effects of magnesium sulfate on the excretion of other electrolytes, nor have studies on the renal clearance of magnesium been reported. It is the purpose of this report to present such d...

BACKGROUND Propofol is the most widely used drug in the induction of general anesthesia, however its disadvantages of injection pain has always been a problem for clinical anesthetists. Many strategies have been proposed and magnesium sulfate is one of them. This is the first meta-analysis studies evaluating effects of magnesium sulfate pretreatment for preventing propofol-induced injection pai...

OBJECTIVE Magnesium sulfate is proposed to have neuroprotective effects in the offspring. We examined the effects of maternal magnesium sulfate administration on maternal and fetal inflammatory responses in a rat model of maternal infection. STUDY DESIGN Pregnant rats were injected with saline, Gram-negative bacterial endotoxin lipopolysaccharide or lipopolysaccharide with magnesium sulfate (...

BACKGROUND Pre-eclampsia/eclampsia is one of the most common causes of maternal and perinatal morbidity and mortality in low and middle income countries. Magnesium sulfate is the drug of choice for prevention of seizures as part of comprehensive management of the disease. Despite the compelling evidence for the effectiveness of magnesium sulfate, concern has been expressed about its safety and ...

at the present, many drugs are used for inhibition of uterine contractions, but the proportions of preterm labors are increasing. although magnesium sulfate is the most commonly prescribed parenteral tocolytic agent, but its optimal use has yet to be delineated. in this study a high-dose protocol for magnesium sulfate tocolytic therapy was compared with a low-dose regimen. one-hundred patients ...