A male Afro-descendant patient, 57 years old, complaining of polyarticular involvement and weight loss for 18 months, with a load of 13.5 pack years of smoking. On physical examination there was pain on palpation of the right knee and right leg, with signs of inflammation on the knee. We also observed digital clubbing in all fingers. Antinuclear antibodies (ANA) and anti-Sm antibodies were posi...

INTRODUCTION There are conflicting reports in literature about correlation of CSF viral RNA levels with neurological manifestations in HIV positive patients. Many studies in animals and human subjects have shown that CSF HIV-1 RNA can be useful as a specific marker of HIV induced neuropathology. To the contrary there are studies which show that neurological disease states can occur in absence o...

Interleukin-33 (IL-33), a newly described member of the IL-1 family, is located on chromosome 9p24, a chromosomal region of interest in Alzheimer's disease (AD) defined by many genome-wide studies. Three intronic rs1157505, rs11792633, and rs7044343 single nucleotide polymorphisms (SNPs) within IL-33 have recently been reported to be associated with risk of AD in Caucasian populations. In order...

Previous studies have shown a preferential loss of grey matter in fronto-temporal regions in patients with multiple sclerosis. Studies of correlates of disease severity are more controversial, because some studies have suggested an association between sensorimotor cortex atrophy and Expanded Disability Status Scale score, while others did not find such a correlation. The objective of this study...

demographic transformation of the managerial and professional workforce has taken place in the last 50 years. For example, nearly twofifths of all managers and professionals in the United States now are women (Bond, Thompson, Galinsky, & Prottas, 2002), many of whom juggle high involvement in caregiving with work. In addition, fathers have significantly increased their involvement in household ...

Fairness may be a desirable property of a nonrepudiation service. Protocols can achieve fairness through the involvement of a trusted third party but the extent of the trusted third party's involvement can vary between protocols. Hence, one of the goals of designing an efficient non-repudiation protocol is to reduce the work load of the trusted third party. In this paper we present a variant of...

Complex skill acquisition by performing authentic learning tasks is constrained by limited working memory capacity (Baddeley, 1992). To prevent cognitive overload, task difficulty and support of each newly selected learning task can be adapted to the learner’s competence level and perceived task load, either by some external agent, the learner herself, or both. Health sciences students (N = 55)...

conclusions: this study showed acceptable sensitivity and specificity of qtcd and qtd in comparison to lvmi; it seems that standard ecg can be used for early diagnosis of cardiac involvement in asymptomatic patients with thalassemia major. patients and methods: in a case-control study, 60 patients older than ten years of age with thalassemia major who received regular blood transfusion and iron...

breast cancer is a major cause of mortality in women due to malignant diseases and is the most prevalent type of cancer in western countries. according to investigations which has been done in iran so far, the prevalence of disease in our country is also very high, therefore complete attention to clinical and pathological findings of this disease would be extremely essential. in this study, the...