background: to evaluate the present status of blood utilization and develop practice guidelines in teaching hospitals in northern iran. methods: we retrospectively analyzed the amount of blood prepared and used preoperatively for 11 elective procedures, from march 2010 to march 2011 in teaching hospitals in northern iran. study variables included the crossmatch transfusion ratio, the transfusio...

our previous studies on thalassemia patients, homozygous or compound heterozygous for severe beta thalassemia mutations, has suggested that 5’hs4-lcr and/or xmn1-hbg2 backgrounds, which were linked in our thalassemia patients, are important in determining the blood transfusion dependency of these individuals. while the majority of patients with aa/-- 5’hs4/xmn1 background, were severely depende...

abstract introduction anemia in preterm infants is identified as hemoglobin lower than 7-10g/dl around 1-3 months after birth. the aim of this study was to evaluate the effect of early subcutaneous administration of erythropoietin on hematopoiesis and weight gain velocity in preterm infants. materials and methods the present study was clinical trial carried out on 42 preterm infants. those whos...

abstract background beta-thalassemia is a common hereditary hemoglobinopathy, which is a reason of microcytic hypochromic anemia. patients with major thalassemia require multiple blood transfusions. this study evaluated growth in thalassemic patient and relationship with ferritin level. materials and methods this is a cross sectional study on seventy patients (36 boys, 34girls) with transfusion...

BACKGROUND Increasing blood supply safety is one of the most important goals of blood services in the world. In this study, we reviewed the prevalence rate and the trends of three main infections in whole blood donations and strategies for improving blood safety in Yazd blood transfusion center, Iran. MATERIALS AND METHODS In this cross sectional study, data on hepatitis B, C and HIV infectio...

In this study, we report the prevalence of Yesinia Yop-specific IgA antibodies in Iranian healthy blood donors. To our knowledge, this report is the first of its kind from Iran. Yersinia enterocolitica is an animal bacterial species that led to foodtransmitted infections(1) and is major cause of septicemia after transfusion of blood products (2, 3). Mortality rate has been reported 59% in blood...

Background: To evaluate the present status of blood utilization and develop practice guidelines in teaching hospitals in Northern Iran. Methods: We retrospectively analyzed the amount of blood prepared and used preoperatively for 11 elective procedures, from March 2010 to March 2011 in teaching hospitals in Northern Iran. Study variables included the crossmatch transfusion ratio, the transfusi...

BACKGROUND Although apoptosis occurs in nucleated cells, studies show that this event also occurs in some anucleated cells such as platelets. During storage of platelets, the viability of platelets decreased, storage lesions were observed, and cells underwent apoptosis. We investigated the effects of caspase-3 inhibitor on the survival and function of platelets after different periods of storag...

one of the most fundamental components of healthcare system on each country is blood supply chain management. this chain is comprised of two significant components including collecting donor’ bloods and supplying blood’s products. the main purpose of this paper is to concentrate on supplying blood products and present a novel constrained bi-objective mathematical model for a two-echelon blood s...

background and objectives: hepatitis e virus (hev) is a major public health concern in developing countries. hev transmission occurs primarily by the fecal-oral route. it has also been reported that blood donors are potentially able to cause transfusion-associated hepatitis e in endemic areas. this study aimed to determine the seroprevalence of hev infection among volunteer blood donors in cent...