نتایج جستجو برای: irs 1c
تعداد نتایج: 16581 فیلتر نتایج به سال:
To clarify the roles of insulin receptor substrate (IRS) family proteins in phosphatidylinositol (PI) 3-kinase activation and insulin actions in adipocytes, we investigated the intracellular localization of IRS family proteins and PI 3-kinase activation in response to insulin by fractionation of mouse adipocytes from wild-type and IRS-1 null mice. In adipocytes from wild-type mice, tyrosine-pho...
Phosphorylation of insulin receptor substrate (IRS)-2 on tyrosine residues is a key event in IGF-1/insulin signaling and leads to activation of the PI 3-kinase and the Ras/MAPK pathway. Furthermore, phosphorylated serine/threonine residues on IRS-2 can induce 14-3-3 binding. In this study we searched IRS-2 for novel phosphorylation sites and investigated the interaction between IRS-2 and 14-3-3...
هدف از این مطالعه بررسی تغییرات سطح جنگل حوزه شهرستان ایلام از سال 1344 تا 1385 است. نقشه کاربری اراضی مربوط به سال 1344 از روی فتوموزائیک رقومی به دست آمده از عکس های هوایی 20000/1 تهیه شد. برای تهیه نقشه پوشش و کاربری راضی سال 1385 از داده های ماهواره ای سنجنده liss iii ماهواره irs-1c استفاده شده است. پس از بررسی کیفیت رادیومتری و هندسی تصاویر ماهواره ای و تصحیح آن ها، برای استخراج بهتر اط...
Serine phosphorylation of insulin receptor substrate-1 (IRS-1) inhibits insulin signal transduction in a variety of cell backgrounds, which might contribute to peripheral insulin resistance. However, because of the large number of potential phosphorylation sites, the mechanism of inhibition has been difficult to determine. One serine residue located near the phosphotyrosinebinding (PTB) domain ...
Insulin receptor substrate 1 (IRS-1) is a major substrate of insulin, insulin-like growth factors, and cytokine signaling and plays an important role in mediating apoptosis, cell differentiation, and cell transformation. We found that IRS-1 is constitutively activated in a variety of solid tumors, including breast cancers, leiomyomas, Wilms' tumors, rhabdomyosarcomas, liposarcomas, leiomyosarco...
IRS-III is the first WSMO compliant system for supporting the Semantic Web Services technologies and it is based on the IRS-II [3]. This paper presents how we integrated the OWL-S [5] service description ontology to IRS-III. We describe how the underlying model of IRS-III supports OWL-S.
Integrating Interactive Response System (IRS) with a classroom computer is an inexpensive and promising means to overcoming or alleviating obstacles of in-class teacher-student and peer interactions. Unfortunately, such potential applications are often neglected. Accordingly, this study identifies IRS’s features, investigates the merits and limitations of applying existing IRSs to instruction a...
IRS-III is the first WSMO compliant system for supporting the Semantic Web Services technologies and it is based on the IRS-II [3]. This paper presents how we integrated the OWL-S [5] service description ontology to IRS-III. We describe how the underlying model of IRS-III supports OWL-S.
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