The structure of the haemagglutinin-esterase-fusion (HEF) glycoprotein from influenza C virus has been determined to 3.2 A resolution by X-ray crystallography. A synthetic mercury-containing esterase inhibitor and receptor analogue, 9-acetamidosialic acid alpha-thiomethylmercuryglycoside, was designed as the single isomorphous heavy-atom derivative. The asymmetric unit of one crystal form (form...

A novel x-ray diffraction technique, multiple-wavelength anomalous dispersion (MAD) phasing, has been applied to the de novo determination of an unknown protein structure, that of the "blue" copper protein isolated from cucumber seedlings. This method makes use of crystallographic phases determined from measurements made at several wavelengths and has recently been made technically feasible thr...

Diffraction data to 2.7 A resolution were measured on crystals of the homotetramers of components II and III of the cytoplasmic hemoglobin of the symbiont-harboring clam Lucina pectinata. Even though the crystallization conditions are different and the sequence homology of the two hemoglobins is only 63%, the crystals are isomorphous to each other and to the heterotetramer Hb II/III, implying t...

First principles simulations show that the ground state crystal structure of Li4SnS4 is isomorphous to Li4GeS4, in agreement with experiment, and having interstitial sites in void channels along the caxis. The simulations also show that a slightly meta-stable structure (Li4SnS4) is formed by moving Li ions from their central sites to the interstitial positions, consistent with X-ray patterns re...

Crystals of human oxyhaemoglobin were obtained from poly(ethylene glycol) solutions. Spectroscopic and spectrophotometric measurements on the solutions during crystallization and on the dissolved crystals indicate that the method yields stable crystals of oxyhaemoglobin. Preliminary X-ray studies showed that the crystals obtained are isomorphous with those of deoxyhaemoglobin obtained from poly...

In the title compound, [Tb(2)(C(4)H(4)O(4))(C(8)H(4)O(4))(2)](n), the coord-in-ation around each Tb atom is distorted square-anti-prismatic. The benzene-1,4-dicarboxyl-ate and succinate anions bridge the anti-prisms, forming a three-dimensional network. The succinate anion is located on a centre of inversion. The structure is isomorphous with the Dy, Gd, Er and Nd complexes.

High-pressure behaviours of isomorphous HoMn(2)O(5) and BiMn(2)O(5) (Pbam, Z = 4) were studied, using Raman spectroscopy and single-crystal x-ray diffraction, with the samples in diamond anvil cells pressurized to 10.09 GPa and 8.54 GPa, respectively, at room temperature. No phase transition was detected in either material. The two manganates are most compressible along the a axis with the latt...