A novel 31P NMR method for the determination of purity for the military nerve agents sarin, soman, and VX has been developed. In contrast to more conventional quantitative NMR methods, stem coaxial inserts are placed into the sample tube to introduce reference material into the analysis without mixing or reaction with the analyte. All sample preparation is eliminated, and the analysis is comple...

Introduction: Radiochemical purity (RCP) is a routine quality control test carried out at nuclear medicine to determine the concentration of various chemical species present in the radiopharmaceuticals (RPs). The present work describes three years of experience in a single institute for the measurement of these impurities in the RPs preparations. Methods: </strong...

A robust, sensitive, and stability-indicating rapid resolution liquid chromatography method for the simultaneous determination of process impurities and degradation products of lercanidipine hydrochloride in pharmaceutical dosage form was developed and validated. The chromatographic separation was performed on the Zorbax SB C18 [(50 × 4.6) mm] 1.8 μm column, using gradient elution of a potassiu...

A chemical treatment for preparing high purity selectively oxidised SWNTs while preserving optical/ electronic properties of the material has been developed. Efficient removal of both metal and carbonaceous impurities has been demonstrated by AFM, TEM, Raman and absorption spectroscopy, while XPS confirmed quantitative conversion of oxidised defects to functionalisable carboxylic acid groups. F...

The Be-based materials with many particular properties lead to an important research subject. The investigation progresses in the fabrication technologies are introduced here, including main three kinds of Be-based materials, such as Be–Cu capsule, Be2C ablator and high-purity Be material. Compared with the pioneer workgroup on Be-based materials, the differences in Be–Cu target fabrication wer...

In the last 15 years NMR has become a reference technique for the determination of purity for organic standards containing NMR active nuclei [1, 2]. The puzzle proposed for this Analytical Challenge was focused on the use of 1H-NMR for the characterization of a phenylbutazone standard. Such material was purchased from Sigma-Aldrich and analyzed in parallel by HPLC-UV and 1H-NMR. Initially, appl...

One subjective and two objective methods were used to determine the color of reconsti tuted frozen concentrated orange juice. The USDA color scores for 21 samples ranged from 32 to 37 points when this subjective method was used. Two objective methods were used: (a) the Hunter Color and Color Difference Meter to ob tain tristimulus color values and (b) the Bausch and Lomb Spectronic 505 recordin...

High-purity germanium compounds (e.g. germanium dioxide) are used these days in several applications (e.g. germanium-based detectors, semiconductors, fiber-optic systems). Thus, reliable methods for the routine determination of trace element impurities from germanium compounds must be developed. In this study, inductively coupled plasma mass spectrometry, inductively coupled plasma optical emis...