OBJECTIVES Among the seven subtypes of juvenile idiopathic arthritis (JIA), oligoarticular JIA (oJIA) and psoriatic JIA (psJIA) display a predilection for onset in early childhood. We examined whether meaningful differences in clinical phenotype justify the distinction between these conditions. METHODS We performed a chart review to identify children with psoriatic and non-psoriatic oligoarti...

Introduction Juvenile Idiopathic Arthritis (JIA) is term used to classify a group of heterogeneous pediatric rheumatic diseases. Many of these conditions remain active until adulthood and when patients start to be followed by adult Rheumatologists there may arise some classification problems once AIA (Adult Idiopatic Arthritis) does not exist! Many published papers regarding the transition of J...

OBJECTIVE To investigate the effects of a land-based home exercise programme on pain, functional ability and quality of life in patients with juvenile idiopathic arthritis. DESIGN A randomized, controlled, single-blind study. PATIENTS Eighty-one patients with juvenile idiopathic arthritis participated in this study. METHODS Functional ability, pain, and quality of life were assessed with ...

Objective To investigate if the persistence of systemic features is longer in Hispanic children with systemic juvenile idiopathic arthritis (S-JIA) than in non-Hispanic children with S-JIA and to determine early predictors of systemic and articular

Background Juvenile idiopathic arthritis (JIA) is one of the most common chronic inflammatory diseases in childhood. In adult patients with rheumatoid arthritis there is large body of evidence supporting the presence of insulin resistance (IR) mainly linked to the underlying inflammation; severity and duration of the disease influence insulin sensitivity and increase the risk of developing card...

Background Inflammation has emerged as an important factor that contributes to the development of atherosclerosis and is associated with increased cardiovascular risk. Juvenile idiopathic arthritis (JIA) is a chronic inflammatory condition with its origin in childhood. Its adult form, rheumatoid arthritis, has been associated with an excess of cardiovascular disease even after adjustment for tr...

Background Approximately 5–15% of patients with juvenile idiopathic arthritis belong to a subcategory of enthesitis related arthritis (ERA), which is strongly associated with HLA-B27 and male gender. Recent investigations have suggested markedly low discontinuation rates of antitumour necrosis factor (anti-TNF) agents in those with ERA, in whom reports on long-term efficacy and safety of anti-T...

Introduction Temporomandibular joint (TMJ) involvement is seen very often (17-87%) in children with juvenile idiopathic arthritis that can lead to compromised craniomandibular function, dentofacial aestethics and morphology. Contrast enhanced MRI is the golden standart for diagnosis of TMJ arthritis (Argyropoulou, 2009). Previous studies show that HLA II class alleles may have protective or ris...