The K1 gene of Kaposi's sarcoma-associated herpesvirus (KSHV) encodes a 46-kDa transmembrane glycoprotein that possesses transforming properties, initiates signaling pathways in B cells, and prevents apoptosis. Here, we demonstrate a mechanism for activation of the K1 promoter by the Rta transactivator. Electrophoretic mobility shift assay (EMSA) analysis of the K1 promoter demonstrated that pu...

Vitamin K denotes a group of molecules that are needed for the synthesis of certain proteins, mostly required for blood coagulation. Five isoforms of vitamin K exists: vitamin K1, K2, K3, K4, and K5. Vitamin K1 (phytonadione, CAS number 84-800/81818-54-4) has been widely used in cosmetics as it is claimed to reduce the purpura and hyperpigmentation associated with surgical and laser therapies (...

A gene library of genomic DNA Klebsiella aerogenes of capsular serotype K1 was constructed in E. coli LE392 using the cosmid pMMB33. Culture filtrates of E. coli recombinants were screened by ELISA for extracellular polysaccharides specific for K. aerogenes K1. Extracellular polysaccharide extracts from K. aerogenes K1 and 3% of the E. coli recombinants contained immunoprotective extracellular ...

Beautifully Ordered Balanced Incomplete Block Designs, BOBIBD(v, k, λ, k1, λ1), are defined and the proof is given to show that necessary conditions are sufficient for the existence of BOBIBD with block size k=3 and k1=2 and for k=4 and k1=2 except possibly for eleven exceptions. Existence of BOBIBDs with block size k=4 and k1=3 is demonstrated for all but one infinite family and the non-existe...

Vitamin K1 is the first-line therapy to brodifacoum poisoning. Anaphylactoid reactions may occur anytime during intravenous administration of vitamin K1 injection. Vitamin K1 must be ceased when anaphylactoid reactions emerge, and therapeutic plasma exchange could be a second-line option.

Let S(R) be an o-minimal structure over R, T ⊂ Rk1+k2+l a closed definable set, and π1 : R k1+k2+l → R12 , π2 : R k1+k2+l → R, π3 : R k1+k2 → R2 the projection maps as depicted below.

Wall, Susan M., Pramod Mehta, and Thomas D. DuBose, Jr. Dietary K1 restriction upregulates total and Sch28080-sensitive bicarbonate absorption in rat tIMCD. Am. J. Physiol. 275 (Renal Physiol. 44): F543–F549, 1998.—In tubules from the terminal segment of the inner medullary collecting duct (tIMCD) from rats with chronic metabolic acidosis, our laboratory has shown that bicarbonate absorption (J...