The chromosome numbers and karyotypes of five species the genus Iris distributed in Turkey were analyzed. These taxa are I. aucheri (Baker) Sealy, reticulata var. M. Bieb., persica L., peshmeniana Güner & T. Hall, sarii Schott ex Baker. Two them (I. sari peshmeniana) endemic Turkey. studied determeined as 2n=18 persica), 2n=20 sari), 2n=24 aucheri), 2n=36 reticulata). Haploid lengths varied fro...

A retarded child with multiple malformations was found to have a karyotype 47,XY,de1(11)(11 pter leads to q21:), +mar(11 qter leads to q21::?). The mitotically stable centric marker had no demonstrable C heterochromatin. Phenotype-karyotype correlation and the role of C heterchromatin in phenotypic effects are discussed.

twenty accessions of cultivated grass pea (lathyrus sativus l.) and wild species of lathyrus l.collected from western and southern regions of iran were evaluated for their mitotic metaphase chromosomalcharacteristics. all populations comprising 16 populations of cultivated l. sativus and 4 wild populations oflathyrus l. were diploid, 2n=2x=14 chromosomes. there were significant variations among...

background: in algeria, the data on infertility and its various causes are rare. recently, the introduction of assisted reproduction has allowed expecting that 300000 couples, which represent 7% of couples of reproductive age, face difficulty conceiving a child. knowing that most idiopathic cases are likely to be due to chromosomal abnormalities, we aimed to investigate genetic defects by karyo...

A complex aberrant karyotype consisting of multiple unrelated cytogenetic abnormalities is associated with poor prognosis in patients with acute myeloid leukemia (AML). The European Leukemia Net classification and the UK Medical Research Council recommendation provide prognostic categories that differ in the definition of unbalanced aberrations as well as the number of single aberrations. The a...

To identify cytogenetic risk factors predicting outcome in children with advanced myelodysplastic syndrome, overall survival of 192 children prospectively enrolled in European Working Group of Myelodysplastic Syndrome in Childhood studies was evaluated with regard to karyotypic complexity. Structurally complex constitutes a new definition of complex karyotype characterized by more than or equal...

It is controversial whether acute myeloid leukemia (AML) patients with 20-29% bone marrow (BM) blasts, formerly referred to as refractory anemia with excess blasts in transformation (RAEBT), should be considered AML or myelodysplastic syndrome (MDS) for the purposes of treatment and prognostication. We retrospectively studied 571 de novo AML in patients aged >50 years, including 142 RAEBT and 4...