This chapter presents an algorithm for automatically generating a prototype from multicolor karyotypes obtained via multi-spectral imaging of human chromosomes. The single representative prototype of the color karyotype that is generated represents the analytical integration of a group of karyotypes obtained via Multicolor Fluorescence In Situ Hybridization (MFISH) method. Multicolor karyotypin...

Progeny from a sexual outcross between opposite mating types of Pythium sylvaticum were analyzed for inheritance of RFLP and random amplified polymorphic DNA (RAPD) markers. Although most were inherited in expected Mendelian frequencies, several were not. Pulsed field gel electrophoresis was employed to examine these unexpected patterns of marker inheritance at a karyotypic level. Parental oogo...

Chromosomal localization of ribosomal RNA coding genes has been studied by using FISH (fluorescence in situ hybridization) in 21 species from the genus Chironomus Meigen, 1803. Analysis of the data has shown intra- and interspecific variation in number and location of 5.8S rDNA hybridization sites in 17 species from the subgenus Chironomus and 4 species from the subgenus Camptochironomus Kieffe...

ABC Fax + 41 61 306 12 34 E-mail [email protected] www.karger.com © 2003 S. Karger AG, Basel 0301–0171/03/1032–0128$19.50/0 Accessible online at: www.karger.com/cgr Abstract. The karyotypes of three species of sphaerodactyl gekkonid lizards are described after conventional and differential staining. Karyotypes of Gonatodes humeralis and G. hasemani are formed by a gradual series of 32 acrocentri...

We studied the geographical distribution of species, chromosomal, and molecular forms of the Anopheles gambiae Giles (Diptera: Culicidae) complex in 23 sites in Cameroon, Central Africa. Almost all the specimens collected in the four northern-most arid sites were Anopheles arabiensis. Anopheles melas was found in a rural locality surrounded by mangrove swamps, on the Atlantic Coast. In total, 1...

Current genetic and epigenetic theories of cancer-specific drug resistance do not adequately explain: (i) the karyotypic changes that coincide with resistance, (ii) the high rates at which cancer cells acquire and enhance resistance compared to the rates of conventional mutation, (iii) the wide ranges of resistance such as multidrug resistance, (iv) the frequent occurrence of intrinsic drug res...

The C-banding karyotype of the jerboas Allactaga tetradactyla, Jaculus jaculus jaculus, and Jaculus orientalis was described and interspecific relationships were discussed. Despite the conservation of a relatively small amount of C-heterochromatin located at the centromeric region of some chromosomes in all karyotypes, a striking loss of C-heterochromatin was clearly observed in J. orientalis. ...

Abstract Study question Analyze the concordance between nanopore sequencing and MaReCs to validate feasibility of in distinguishing normal embryos from carrier PGT-SR cycles. Summary answer Nanopore is a powerful strategy for accurately nontranslocation translocation precisely localizing breakpoints. What known already Balanced reciprocal (BRT) one most common chromosomal abnormalities that cau...

To further define the cytogenetic differences between B-cell lineage (B-lineage) acute lymphoblastic leukemia (ALL) and T-cell lineage ALL (T-ALL) and to determine the prognostic value of cytogenetics in childhood T-ALL, the blast cell karyotypes of 343 cases of pediatric T-ALL, the largest series reported to date, were evaluated. Cytogenetics were performed in a single central laboratory, and ...

To determine whether ultrasonographic findings can predict the karyotype of spontaneous abortions, 137 pregnancies (54 spontaneous, 83 assisted ovulatory cycles) that subsequently aborted and had chromosome analysis performed on the products of conception were studied ultrasonographically. Transvaginal ultrasound was performed using an Acuson 128XP/10 with 7.5 MHz probe. The numbers of empty ge...