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Abstract Introduction Sleep disturbance from obstructive sleep apnea (OSA) impairs overnight memory processing. This may be mediated by changes to slow wave (SWS) as less activity (SWA) is associated with worse spatial and declarative memory. We developed a within-subjects model of SWS-specific CPAP-withdrawal create 3 polysomnologically (PSG)-verified conditions 1) stable-SWS on CPAP, 2) SWS-f...
Numerous studies have demonstrated the efficacy of CPAP therapy for reducing symptoms (eg, daytime sleepiness), improving quality of life (QOL), reducing the risk of driving and occupational accidents, and preventing sequelae of obstructive sleep apnea (OSA), such as cardiovascular morbidity and mortality.1-3 Many patients have trouble complying with CPAP therapy even though it is effective.4 A...
BACKGROUND Adherence to short-term continuous positive airway pressure (CPAP) may predict long-term use. Unfortunately, initial CPAP intolerance may lead to poor adherence or abandonment of therapy. OBJECTIVE To determine whether a short course of eszopiclone at the onset of therapy improves long-term CPAP adherence more than placebo in adults with obstructive sleep apnea. DESIGN Parallel r...
BACKGROUND Rates of fresh gas flow (FGF) commonly used when continuous positive airway pressure (CPAP) is delivered by face mask theoretically reduce the delivery and availability of therapeutic aerosols. As it may be hazardous for patients with acute respiratory failure to interrupt mask CPAP, the effects of CPAP on aerosol kinetics and bronchodilator efficacy were investigated. METHOD The e...
BACKGROUND Obstructive sleep apnea is associated with an increased risk of cardiovascular events; whether treatment with continuous positive airway pressure (CPAP) prevents major cardiovascular events is uncertain. METHODS After a 1-week run-in period during which the participants used sham CPAP, we randomly assigned 2717 eligible adults between 45 and 75 years of age who had moderate-to-seve...
STUDY OBJECTIVES We studied the effect of continuous positive airway pressure (CPAP) treatment on sympathetic nervous activity in 38 patients with obstructive sleep apnea. DESIGN Randomized, placebo-controlled trial. SETTING Patients underwent polysomnography on three occasions in a clinical research center, and had BP monitored over 24 h at home. All of the patients had sleep apnea with a ...
Early gain in body mass with continuous positive airway pressure therapy for obstructive sleep apnea
Zusammenfassung Somnologie 2010 · 14:207–212 DOI 10.1007/s11818-010-0483-8 © Springer-Verlag 2010 R.E. Bourey · J.R. Bourey · N. Habbal · A. Balaa Early gain in body mass with continuous positive airway pressure therapy for obstructive sleep apnea. Early body mass gain with CPAP therapy Abstract Study objectives. Many clinicians believe that continuous positive airway pressure (CPAP) therapy of...
Introduction: Only vindication of a nasal continuous positive airway pressure (CPAP) retitration procedure will be an actual change in the optimal CPAP pressure after that test. The purpose of this study was to identify any items in patient characteristics, clinical features, baseline PSG and initial CPAP titration as predictors of change in optimal pressure on CPAP retitration. Methods: 46 pat...
Previous preliminary results have shown an overnight decrease in haematocrit and red cell count after the first night of treatment with nasal continuous positive airway pressure (CPAP) in obstructive sleep apnoea (OSA) patients. The present study was designed to confirm these preliminary data, and to analyse the long-term effects of CPAP. The haematocrit and red cell count (RCC) were measured i...
OBJECTIVE To determine the safety and efficacy of nasal continuous positive airway pressure (CPAP) for obstructive sleep apnea (OSA) during childhood and the effects of growth and maturation on CPAP requirements. DESIGN Retrospective study with use of a written questionnaire administered to pediatric practitioners treating sleep disorders. SETTING Nine academic pediatric sleep disorders cen...
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