Ovarian cancer (OC) is the most lethal gynecological cancer. Multiple genetic and epigenetic abnormalities have been detected in ovarian cancers. As microRNAs (miRNAs) play important roles carcinogenesis, numerous researchers aim to determine molecular mechanism that regulates cells proliferation metastasis. In current study, expression of microRNA-613 related KRAS Ezrin genes was assessed by R...

Objectives Single nucleotide polymorphisms in microRNAs (microRNA-196a2 rs11614913, microRNA-146a rs2910164, microRNA-149 rs2292832 and microRNA-499 rs3746444) have been inconsistently associated with risk for oral squamous cell cancer (OSCC). This meta-analysis aimed to assess the correlation between microRNA polymorphisms and susceptibility to OSCC. Materials and Methods Free words were use...

Many of the known microRNAs are encoded in polycistronic transcripts. Here, we reconstruct the evolutionary history of the mir17 microRNA clusters which consist of miR-17, miR-18, miR-19a, miR-19b, miR-20, miR-25, miR-92, miR-93, miR-106a, and miR-106b. The history of this cluster is governed by an initial phase of local (tandem) duplications, a series of duplications of entire clusters and sub...

BACKGROUND It is controversial whether microRNA-126 is a tumor suppressive or oncogenic miRNA. More experiments are needed to determine whether microRNA-126 is associated with non-small cell lung cancer risk and prognosis. METHODS Over-expression of microRNA-126 was performed to evaluate the cell invasion and tumor growth in non-small cell lung cancer (NSCLC) cell lines and nude mouse xenogra...

To explore the effect of circular RNA_0025033 on proliferation, migration and invasion cervical cancer HeLa cells its molecular mechanism. The tissues adjacent 39 patients with in our hospital from January 2017 to December 2020 were selected. expression levels microRNA-1256 detected by Quantitative reverse transcription polymerase chain reaction. Cell counting kit 8 was used detect cell viabili...

To investigate the influence of harpagide isolated from Scrophularia ningpoensis Hemsl. on human umbilical vascular endothelial cells damage induced by oxidized low-density lipoprotein and its possible mechanism. Human were cultured in vitro. Different doses (20, 40, 80 μmol/l) applied to treat lipoprotein, overexpressing microRNA-140-5p μg/ml was with downregulation. Enzyme-linked immunosorben...

This paper proposes an emotion recognition system. Human emotion can be expressed through many kinds of medium such as speech, image, facial expression, and so forth. This paper focuses on the textual data of them. Proposed system is a hybrid system that uses alternatively two methods, keyword-based and machine learning method. Keyword-based methods are traditional approaches using emotional ke...

Infrared Functional Imaging was applied to the study of Raynaud’s Phenomenon obtaing a simultaneous assessment of the thermal properties of all five fingers of both hands of a group of patients with respect of a control group. The method is based on the use of high-resolution telethermography imaging and allows identification of objective parameters from the re-warming curves of finger immediat...