Peroxisome proliferator-activated receptor γ (PPARγ, NR1C3) and testicular receptor 4 nuclear receptor (TR4, NR2C2) are two members of the nuclear receptor (NR) superfamily that can be activated by several similar ligands/activators including polyunsaturated fatty acid metabolites, such as 13-hydroxyoctadecadienoic acid and 15-hydroxyeicosatetraenoic acid, as well as some anti-diabetic drugs su...

Two eight-state 7-bit soft-output Viterbi decoders matched to an EPR4 channel and a rate-8/9 convolutional code are implemented in a 0.18m CMOS technology. The throughput of the decoders is increased through architectural transformation of the add-compare-select recursion, with a small area overhead. The survivor-path decoding logic of a conventional Viterbi decoder register exchange is adapted...

High-speed TCP/IP networks, capable of supporting several 10 Mb/s data streams, are in common use within the continental United States and are being introduced in Europe. Extending such networks to support the intercontinental research community will require the solving of several technical challenges, including those at the transport level and those in congestion control and buffering within p...

A recently carried out unitarity based analysis [1, 2] involving the evaluation of Jarlskog’s rephasing invariant parameter J as well as the evaluation of the angles α, β and γ of the unitarity triangle is extended to include the effects of K − K̄ as well as B − B̄ mixings. The present analysis attempts to evaluate CP violating phase δ, |Vtd| and the angles α, β and γ by invoking the constraints ...

Ab&ructWith the growing demand for high-speed transmission of digital data, there is a challenge for utilizing the existing copper plant as the transmission medium, especially for shorthop links. This medium offers a lower cost to a fiber medium, but requires more sophisticated electronics to account for electromagnetic emissions, cross-talk, and cable loss. These include pulse shaping filters,...

Acquisition of resistance to docetaxel (Doc) is one of the most important problems in treatment of breast cancer patients, but the underlying mechanisms are still not fully understood. In present study, Doc-resistant MDA-MB-231 and MCF-7 breast cancer cell lines (MDA-MB-231/Doc and MCF-7/Doc) were successfully established in vitro by gradually increasing Doc concentration on the basis of parent...

objective(s): nowadays, cancer is an important public health problem in all countries. limitations of current chemotherapy for neoplastic diseases such as severe adverse reactions and tumor resistance to the chemotherapeutic drugs have been led to a temptation for focusing on the discovery and development of new compounds with potential anticancer activity.   materials and methods: a new series...

With increasing awareness of reduction of energy and CO2 footprint, more waste is considered recyclable for generating value-added products. Here we reported the negatively-valued iron mud, a waste from groundwater treatment plant, was successfully converted into magnetic adsorbent. Comparing with the conventional calcination method under the high temperature and pressure, the synthesis of the ...