نتایج جستجو برای: khalil mardom bak

تعداد نتایج: 3778  

Journal: :Journal of cell science 2016
Stephanie Einsele-Scholz Silke Malmsheimer Katrin Bertram Daniel Stehle Janina Johänning Marianne Manz Peter T Daniel Bernhard F Gillissen Klaus Schulze-Osthoff Frank Essmann

The pro-apoptotic multidomain Bcl-2 proteins Bax and Bak (also known as BAK1) are considered the gatekeepers of the intrinsic pathway of apoptosis by triggering the mitochondrial release of cytochrome c The role of the third Bax- and Bak-homologous multidomain protein Bok, however, is still unresolved. As cells doubly deficient for Bax and Bak are largely resistant to various apoptotic stimuli,...

2002
KENT GUSTAVSON RICHARD M. HUBER Richard M. Huber

This chapter summarizes the results of five years of research supported by the World Bank Research Committee, and from Trust Funds from the Netherlands, Sweden and Canada administered by the World Bank. The research was done under the direction of Richard M. Huber (World Bank), task team leader, with input from numerous researchers as referenced throughout this chapter. Primary input was provid...

Journal: :Nature Reviews Molecular Cell Biology 2001

Journal: :Tidsskrift for Den norske legeforening 2010

Journal: :Potensi : Jurnal Sipil Politeknik 2015

Journal: :Tidsskrift for Den norske legeforening 2014

Journal: :Tidsskrift for Den norske legeforening 2015

Journal: :The EMBO journal 2016
Grant Dewson

How the two killer proteins Bax and Bak form the putative “apoptotic pore” that is responsible for irrevocably damaging mitochondria leading to cell death during apoptosis is considered the “holy grail” of apoptosis research. Indeed, even whether Bax and Bak form a pore remains contentious largely due to the failure to detect such structures in cells or mitochondria. Two new super-resolution mi...

Journal: :Tidsskrift for Den norske legeforening 2015

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