Therefore, the need for early and even frontline use of anti-TNF agents has been proposed for CD patients. In a study that compared the efficacy of IFX monotherapy, AZA monotherapy, and a combination of the two drugs in adults with moderate-to-severe CD who were previously naïve to immunosuppressive or biologic therapies, patients treated with IFX monotherapy were more likely to have a corticos...

This article is part of a Minifocus on the ESCRT machinery. For further reading, please see related articles: ‘No strings attached: the ESCRT machinery in viral budding and cytokinesis’ by Bethan McDonald and Juan Martin-Serrano (J. Cell Sci. 122, 2167-2177) and ‘How do ESCRT proteins control autophagy?’ by Tor Erik Rusten and Harald Stenmark (J. Cell Sci. 122, 2179-2183). The endosomal sorting...

BACKGROUND Only 39% of deliveries in Pakistan are attended by skilled birth attendants, while Pakistan's target for skilled birth attendance by 2015 is > 90%. METHODS A 12-month maternal health voucher intervention was implemented in Dera Ghazi Khan City, located in Southern Punjab, Pakistan in 2009. A pre-test/post-test non-experimental study was conducted to assess the impact of the interve...

Objective: To evaluate the frequency, common presentation, anti-snake venom (ASV) related management and outcome of snake bite cases in admitted children at a tertiary care hospital. Study Design: Case-series study. Setting: Department Pediatric, Dera Ghazi Khan Medical College (DGKMC) & Hospital. Period: 1st March 2021 to 31st August 2021. Material Methods: During study period, all present...

INSPIRATION Investigators; Saeideh Mazloomzadeh; Shiva Khaleghparast; Behshid Ghadrdoost; Mostafa Mousavizadeh; Mohammad Reza Baay; Feridoun Noohi; Hamidreza Sharifnia; Arezoo Ahmadi; Sasan Tavan; Nasser Malekpour Alamdari; Fathi; Mahshid Soleimanzadeh; Mostafa; Navid Davoody; Maryam Zarinsadaf; Sara Tayyebi; Fahimeh Farrokhzadeh; Faeze Nezamabadi; Esmaeil Soomari; Parham Sadeghipour, MD; Azita...

Northern Koh Sulaiman foldbelt, Shirani, North and South Waziristan (South Punjab, Balochistan Khyber Pakhtunkhwa) comprised mostly PermoTriassic to Recent sediments with subordinate igneous metamorphic rocks. These sedimentary strata folded faulted by geodynamic tectonic forces occurred during Late Cretaceous revealed through anticlinal synclinal foldings active faultings. The areas host many ...

satisfaction with nursing care and related factors in hospitalized cancer patients in shahid ghazi hospital in tabriz     mogadasiyan s [1] , abdolahzadeh f [2] , rahmani a [3] ,nikanafar ar [4] , firoziyan aa [5] *     received: 5 may, 2013 accepted: 3 aug , 2013     abstract   background & aims : patient satisfaction with nursing services provided as an indicator of the quality of nursing car...

Congenital malformations are among the most distressing diseases that affect mankind. Attempts to reconstruct the major anomalies have only limited success. Malformations affecting the brain are usually associated with some degree of mental deficiency. The recognition of causative agents such as infection, drugs, and genetic abnormalities offers some hope toward their prevention. Unfortunately ...

Notopterus chitala is a member of the primitive teleost lineage and considered as commercially important food fish. To study concentration sodium potassium influence fish size condition factor on bioaccumulation these macro-elements, total 16 specimens N. were collected from River Indus. Mean (±SD) body weight, length was found 250.32±113.93 g, 32.93 ± 4.85 cm 0.647± 0.094. Fish samples oven dr...