The lactoperoxidase (LPO) antibiotic system is a well-characterized component of mammary and salivary gland secretions. Because LPO has been shown to function in ovine airways, human airway tissue and secretions were examined for the presence of LPO and its substrate, the anion thiocyanate (SCN-). In addition, human airway secretions were tested for LPO-mediated antibacterial activity, and LPO'...

The permeability of junctional complexes to ultrastructural tracers of different molecular weight and the freeze-fracture appearance of junctional structure were investigated in the resting and stimulated rat parotid gland. Tracers were administered retrogradely via the main excretory duct, and allowed to flow by gravity (16 mmHg) into the gland for 15-60 min. Secretion was induced in some anim...

"After obtaining my PhD in biochemistry with CM. Edelman, I went to the laboratory of G.J.V. Nossal at the Walter and Eliza Hall Institute as a postdoctoral fellow to learn cellular immunology. At the time I joined the laboratory, Nossal and G.L. Ada were carrying out a series of studies using radioiodinated protein antigens designed to ascertain the distribution of antigen in lymphoid tissues ...

Lactoperoxidase (LPO E.C. 1.11.1.7) is a member of the peroxidase family and an important glycoprotein containing heme group in its structure showing antimicrobial effect on disease causing microorganisms digestive system newborn babies. Thiazoles are simplest members heterocyclic compounds nitrogen sulfur atoms their structure. Many active pharmaceutical substances such as vitamin B1, penicill...

Minimally processed lettuce is sensitive to microbial attack caused by the loss of natural resistance and their high water content and nutrients. The use of natural anti-microbial agents such as the lactoperoxidase system (LPS) represents an interesting alternative to the use of chemical treatments. This study focused on the importance of LPS and its efficiency as a bioprotective agent. The eff...