To assess the severity of hemolysis and to determine whether severity of hemolysis was related to type of prosthesis, hematocrit readings (Hct), schistocyte counts (S), reticulocyte counts (R), and determinations of haptoglobin (Hp), lactic acid dehydrogenase (LDH), bilirubin, urinary hemoglobin, and urinary hemosiderin (Hs) were performed on 54 patients who had three different types of aortic ...

In this study, we evaluate a method for the early diagnosis of radiodermatitis for use in the prevention and therapy of this condition. Hairless mice (SKH1-hr) were used to study the early diagnosis of radiodermatitis. Lactate dehydrogenase (LDH, EC 1.1.1.27) isozymes were analyzed using native-polyacrylamide gel electrophoresis and western blotting of blood serum and tissues collected from SKH...

To assess the effects of phenytoin sodium on biochemical markers of testicular function. Male Wistar rats (12 weeks old) were treated with phenytoin and sacrificed at the end of 2, 4, 5, 7, 10 and 15 week after the last exposure to phenytoin sodium. The testes were removed, weighed and processed for biochemical analysis. The intratesticular testosterone level was significantly (P<0.001) reduced...

OBJECTIVES The neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR) have been proved to affect the prognosis of various types of cancers. However, the prognostic role of NLR and PLR in patients with small-cell lung cancer (SCLC) remains controversial. The objective of this study is to assess the prognostic values of NLR, PLR and other potential prognostic indexes in SCLC pa...

F1 offspring of the African cichlid Pseudocrenilabrus multicolor victoriae Seegers, 1990 from swamp (low oxygen) and lake (high oxygen) origin were raised under normoxia and submitted to hypoxia acclimation (0.8 ± 0.4 mg L–1) and normoxia acclimation (7.4 ± 0.3 mg L–1) for 4 weeks. Haematocrit and lactate dehydrogenase (LDH) specific activities in the liver, white skeletal muscle, heart, and br...

A highly oriented film was fabricated by layer-by-layer self-assembly of DNA and MgAl-layered double hydroxide nanosheets, and its application in chiroptical switch was demonstrated via intercalation and deintercalation of an achiral molecule into the DNA cavity. DNA molecules are prone to forming an ordered and dispersive state in the interlayer region of rigid layered double hydroxide (LDH) n...

Carborane-intercalated layered double hydroxide nanohybrids (CB-LDH) and a magnesium ferrite (MF) supported-CB-LDH core-shell nanocomposite (CB-LDH@MF) are reported. The preparation of nanohybrids were carried out by exchanging the interlayer nitrate groups of Mg-Al-NO3-LDH with monothiol-o-carborane (SCB), 1-methyl-2-carboxyl-o-carborane (MeCB), 1-phenyl-2-carboxyl-o-carborane (PhCB) and 1,12-...

Background: It is expected that the expression of key enzymes glycolysis pathway, specially PFK-1, increases tumor cells and so enhances function this pathway. The p53 HIF-1 proteins are regulators PFK-1 LDH enzymes. This study was performed to investigate changes in LDH-A, p53, HIF-1α genes identify metabolic non-small cell lung carcinoma (NSCLC) samples. Methods: A number 30 tumors their adja...

Objective. To identify blood biomarkers to predict severity and mortality in AIDS PCP patients. Methods. Biomarkers including clinical parameters and plasma inflammatory cytokines were assessed in 32 HIV-infected patients with Pneumocystis pneumonia (PCP) at time of admission. Predictive value of the biomarkers for clinical severity and in-hospital mortality was evaluated by corresponding ROC c...

As an approach to search for chemopreventive agents, we tested p-coumaric acid, 3-methoxy-p-coumaric acid (ferulic acid), and 3,5-dimethoxy-p-coumaric acid (sinapic acid) in B16/F10 melanoma cells. Intracellular melanin contents were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay and cytotoxicity of the compounds were examined by lactate dehydrogenase (LDH) re...