background & aim: evaluation of prevalence of risk factors for breast cancer in different regions of iran and identification of their significant effect on this disease can promote the prevention and reduction of breast cancer incidence. therefore, this study aimed to evaluate the prevalence, demographic characteristics, and frequency of the risk factors of breast cancer during 10 years. method...

background cancer stem cells play crucial roles in resistance to therapeutic schemes and relapse of disease, so it is important to find targeted therapies that kill them selectively. breast cancer is the most common cancer in females living in all part of the world including iran and it has an important burden in public health with direct impact on patients’ families. breast cancer in young adu...

Tuberculosis (TB) of the breast is a rare disease that typically affects women reproductive age, mainly between 15 and 25 years age. TB has non-specific clinical presentation may present as lump, abscess, or sinus, it sometimes mimic cancer. Histological diagnosis necessary to avoid mismanagement potentially curable disease. We case an 18-year-old female with left upper quadrant lump 1-year dur...

breast cancer affects iranian women at least one decade younger than their counterparts in othercountries and the incidence of breast fibroadenoma is growing in the last two decades in tehran. thisstudy aimed to compare the ahr levels in premenopausal breast cancer and breast fibroadnemo withappropriate normal groups. possible associations of ahr with lifestyle and reproductive risk factorsand ...

Metastases to the gastrointestinal tract rarely occur in breast cancer except in invasive lobular carcinoma. The present study reports a rare case of metastatic gastric cancer from invasive ductal carcinoma (IDC) of the breast mimicking primary gastric linitis plastica. A 51-year-old premenopausal female, who had a history of partial mastectomy for right breast cancer at the age of 40, was refe...

conclusions in this study, we proposed a new computer aided diagnostic tool for the detection and classification of breast cancer. the obtained results showed that the proposed method is more reliable in diagnostic to assist the radiologists in the detection of abnormal data and to improve the diagnostic accuracy. results after classification with the ensemble supervised algorithm, the performa...

background: metformin is used to lower blood sugar in patients with type ii diabetes. recent research showed that metformin has effects on cancer cell growth. studies show that metformin can induce apoptosis in certain cancer cell lines. in this study, we examined the effect of metformin on apoptosis in the t47d breast cancer cell line. methods : the t47d breast cancer cell line was selected an...

background: regulatory t cells (t-regs) have an important role in cancer by suppression of protective antitumor immune responses. regulatory t cells express the forkhead/winged helix transcription factor (foxp3) and ox40 molecules which have important regulatory roles in the immune system. objective: to evaluate foxp3 and ox40 transcripts in the peripheral blood mononuclear cells of women with ...

Mammary tuberculosis is a rare clinical entity, often mimicking breast cancer or abscesses. A 26-year-old female presented with a painful left breast mass and an associated sinus tract with purulent discharge. Physical examination revealed a tender, erythematous, firm left breast mass with an associated sinus tract opening with discharge within the upper outer quadrant of her left breast with a...