Introduction Nausea and vomiting are the most common side effects of chemotherapy in the pediatrics with cancer which affect their quality of life. Use of some methods of complementary medicine in leukemia patients is problematic. Because, leukemia patients are at risk of infection and bleeding, therefore the use of acupressure, acupuncture, and deep massage can be risky in these patients. Slow...

purpose: to report a case of acute myelogenous leukemia (aml) presenting with periorbital cellulitis and progressing to facial and neck cellulitis. case report: a 17 year old male patient presented with periorbital cellulitis which progressed to the right hemifacial and neck area. he did not respond to regular antibiotic therapy. peripheral blood smear showed leukocytosis with predominance of i...

micrornas are 19-22 nucleotide rnas involved in such important processes as development, proliferation, differentiation and apoptosis. different mirnas are uniquely expressed in lymphoid t cells, and play a role indevelopment and differentiation of various subtypes by targeting their target genes. recent studies have shown that aberrant mirna expression may be involved in t cell leukemogenesis ...

myeloproliferative neoplasms (mpns) such as polycythemia vera, essential thrombocythemia, primary myelofibrosis and chronic myeloid leukemia have too similar and accurate way to differentiate their is study of genetic disorders in these patients. philadelphia chromosome is a sure way to definitively diagnose cml. recently, jak2v617f mutation introduced as a diagnostic marker for other myeloprol...

objective(s): t-cell acute lymphoblastic leukemia (t-all) is an aggressive hematologic malignant tumor. administration of chemical compounds influencing apoptosis and t cell development has been discussed as promising novel therapeutic strategies. valproic acid (vpa) as a recently emerged anti-neoplastic histone deacetylase (hdac) inhibitor and pioglitazone (pgz) as a high-affinity peroxisome p...

abstract   background : leukemia is one of the mostcommon cancers in children, comprising more than a third of all childhood cancers. newly affected patients in usa are estimated as 10100cases, and if these cases are diagnosed late or proper treatment is not applied, then it can be mortal. because rapid and proper diagnosis of leukemia based on clinical or medicinal findings (without biopsy) is...

leukemia is a blood disease which is caused by the inhibition of differentiation and an increased proliferation rate. nature has been known as a rich source of medically useful substances. high diversity of bioactive molecules extracted from marine invertebrates, makes them ideal candidates for cancer researches. the study has been done to investigate cytotoxic effects of dichloromethane brittl...

background: solid tumors may occur in 3% of the patients with chronic myeloid leukemia (cml). in this paper, we presented a case of cml following treatment of colon cancer. case presentation: a 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...

abstract objective the great majority of patients with childhood leukemia become long-term survivors. they treated with chemotherapy and prophylactic central nervous system (cns) irradiation. the aim of this cross-sectional study was to evaluate effect of the long-term toxicity in all survivors, and possible effects of this treatment on their intellectual in compare with their sibling. material...

abstract objective the incidence of childhood cancer has been increasing nearly one percent per year for the past two decades. leukemia and lymphoma are the most common types of childhood cancers. this study assessed the relation between environmental factors (hydrocarbon, agricultural toxin, insecticide) and leukemia/lymphoma in children, which was evaluated by the frequency of the parents’ ha...