نتایج جستجو برای: leukocyte mycobacterium defect

تعداد نتایج: 173782  

Journal: :Memorias do Instituto Oswaldo Cruz 1997
O Menezes-de-Lima-Júnior G Henriques M das

Mycobacteria, specially Mycobacterium tuberculosis are among the micro-organisms that are increasing dramatically the number of infections with death, all over the world. A great number of animal experimental models have been proposed to investigate the mechanisms involved in the host response against these intracellular parasites. Studies of airway infection in guinea-pigs and rabbits, as well...

Journal: :American journal of respiratory and critical care medicine 2009
Sonia A Gomez Claudia L Argüelles Diego Guerrieri Nancy L Tateosian Nicolás O Amiano Rut Slimovich Paulo C Maffia Eduardo Abbate Rosa M Musella Verónica E Garcia H Eduardo Chuluyan

RATIONALE Human secretory leukocyte protease inhibitor (SLPI) displays bactericidal activity against pathogens such as Escherichia coli and Streptococcus. Furthermore, it has been reported that murine SLPI shows potent antimycobacterial activity. OBJECTIVES The aim of the present study was to investigate whether human recombinant SLPI not only kills mycobacteria but also acts as a pattern rec...

Journal: :Infection and immunity 2010
Kaori Sakamoto Rachel E Geisel Mi-Jeong Kim Bryce T Wyatt Llewelyn B Sellers Stephen T Smiley Andrea M Cooper David G Russell Elizabeth R Rhoades

During inflammatory responses and wound healing, the conversion of soluble fibrinogen to fibrin, an insoluble extracellular matrix, long has been assumed to create a scaffold for the migration of leukocytes and fibroblasts. Previous studies concluded that fibrinogen is a necessary cofactor for mycobacterial trehalose 6,6'-dimycolate-induced responses, because trehalose dimycolate-coated beads, ...

Journal: :Clinical immunology 2008
David J Fitzhugh Siqing Shan Mark W Dewhirst Laura P Hale

Bromelain, a mixture of proteases derived from pineapple stem, has been reported to have therapeutic benefits in a variety of inflammatory diseases, including murine inflammatory bowel disease. The purpose of this work was to understand potential mechanisms for this anti-inflammatory activity. Exposure to bromelain in vitro has been shown to remove a number of cell surface molecules that are vi...

Journal: :Journal of immunology 2001
N M Price J Farrar T T Tran T H Nguyen T H Tran J S Friedland

Tuberculous meningitis is characterized by cerebral tissue destruction. Monocytes, pivotal in immune responses to Mycobacterium tuberculosis, secrete matrix metalloproteinase-9 (MMP-9), which facilitates leukocyte migration across the blood-brain barrier, but may cause cerebral injury. In vitro, human monocytic (THP-1) cells infected by live, virulent M. tuberculosis secreted MMP-9 in a dose-de...

ژورنال: Medical Laboratory Journal 2011
, , Livani S, , Mirinargesi M, , Nemati-Shoja E, , Rafiei S, , Tabarraei A, , Taziki M, ,

Abstract Background and objectives: Identification and monitoring of multidrug-resistant Mycobacterium tuberculosis strains (MDR) is highlighted by the high risk of their spreading in different areas. Prevalence of these strains was evaluated in Golestan province in northeast of Iran. Material and Methods: Drug susceptibility testing to Isoniazid and rifampin was carried out for 148 clinical sa...

ژورنال: یافته 2011
حیدری, فضه, فرنیا, پریسا, مجد, احمد, نوروزی, جمیله,

i Rapiddentification of atypical mycobacterium(Non-tuberculosis mycobacterium NTM) is important because of increase of these organisms infection in recent years. As phenotypic tests are time consuming and expensive, nowadays the molecular methods are widely used for rapid identification of mycobacterium spcies. The aim of this study was molecular differentiation of atypical mycobacteria usin...

Journal: :مجله دانشگاه علوم پزشکی مازندران 0
اعظم رهاوی a rahavi امیرعلی حیدری a.a haidari محمدعلی خلیلی m.a khalili medical student, shahid sadoughi university of medical sciences, yazd, iranدانشجوی پزشکی، دانشگاه علوم پزشکی شهید صدوقی یزد جلال قاسم زاده j ghasemzadeh نسیم طبیب نژاد n tabibnejad

background and purpose: an important factor involved in infertility is reactive oxygen species (ros). ros can damage sperm dna, and involve lipid per-oxidation. ros elevation is under the influence of leukocyte activation. the objective of this study was to evaluate the level of ros as well as leukocyte, in normozoospermic (no) and ologoasthenoteratozoospermic (oat) ejaculates. materials and me...

Journal: :Journal of leukocyte biology 2003
Homayoun Shams Peter F Barnes Stephen E Weis Peter Klucar Benjamin Wizel

Mycobacterium tuberculosis antigens that are recognized by human CD8+ T cells are potentially important vaccine target molecules. We used a motif-based strategy to screen selected proteins of M. tuberculosis for peptides predicted to bind to human leukocyte antigen (HLA)-A*0201. We identified two 10 amino acid peptides that elicited cytolytic T lymphocyte activity and interferon-gamma productio...

2013
Jyotirmay Biswas Reesha Karingattil Ravi Angayarkanni Naryanasamy Lily Therese Kulandai Hajib Naraharirao Madhavan

Eales' disease, first described by the British ophthalmologist Henry Eales in 1880, is characterized by three overlapping stages of venous inflammation (vasculitis), occlusion, and retinal neovascularization. Diagnosis is mostly clinical and requires exclusion of other systemic or ocular conditions that could present with similar retinal features. In recent years, immunological, molecular biolo...

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