Nine new gingerols, including three 6-oxo-shogaol derivatives [(Z)-6-oxo-[6]-shogaol (1), (Z)-6-oxo-[8]-shogaol (2), (Z)-6-oxo-[10]-shogaol (3)], one 6-oxoparadol derivative [6-oxo-[6]-paradol (4)], one isoshogaol derivative [(E)-[4]-isoshogaol (5)], and four paradoldiene derivatives [(4E,6Z)-[4]-paradoldiene (8), (4E,6E)-[6]-paradoldiene (9), (4E,6E)-[8]-paradoldiene (10), (4E,6Z)-[8]-paradold...

Plants display extensive intraspecific variation in secondary metabolites. However, the selective forces shaping this diversity remain often unknown, especially below ground. Using Taraxacum officinale and its major native insect root herbivore Melolontha melolontha, we tested whether below-ground herbivores drive intraspecific variation in root secondary metabolites. We found that high M. melo...

MICHAEL L. GINGER, PAUL G. MCKEAN, RICHARD BURCHMORE and KAREN M. GRANT Faculty of Health and Medicine, Division of Biomedical and Life Sciences, Lancaster University, LA1 4YK, UK Faculty of Health and Medicine, Lancaster Medical School, Lancaster University, LA1 4YA, UK Institute of Infection, Immunity, and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, ...

In the present work, the effective moisture diffusivity and activation energy were calculated using an infinite series solution of Fick’s diffusion equation. The results showed that increasing drying temperature accelerated the drying process. All drying experiments had only falling rate period. The average effective moisture diffusivity values varied from 2.807x10 to 6.977x10m s over the tempe...

Ziliang Ye,1 Shuang Zhang,1 Yuan Wang,1 Yong-Shik Park,1 Thomas Zentgraf,1 Guy Bartal,1 Xiaobo Yin,1,2 and Xiang Zhang1,2,* 1NSF Nanoscale Science and Engineering Center (NSEC), University of California, 3112 Etcheverry Hall, Berkeley, California 94720, USA 2Material Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA (Received 6 January 2012; revised manus...

Taraxacum officinale has been used in Jordan folk medicine to treat male infertility. A recent study has proved a contradictory effect of the whole plant aqueous extract. The aim of the current study was to determine if the leaves of T. officinale have similar anti-fertility activities, and whether this effect is mediated through the regulation of spermatogonial stem cells (SS...

background and objectives: nasturtium officinale w.t.aiton (brassicaceae) is used as an edible vegetable in various parts of iran. the aim of the present study was to investigate the protective activity of the methanolic extract of nasturtium officinale against gamma-radiation-induced hepatotoxicity in terms of histopathological changes. methods: male c57 mice were divided into 10 groups. group...

objective: lamotrigine is an antiepileptic drug, widely used in the treatment of epilepsy; long-term use of this drug can cause hepatotoxicity. zingiber officinale roscoe (ginger) possesses antioxidant properties. in present research, the effect ofhydroalcoholic extract of ginger (heg) on the liver of lamotrigine-treated epileptic rats was investigated material and methods: forty-eight female w...

Ginger is a medicinal plant that has been widely used in Chinese, Ayurvedic and Tibb-Unani herbal medicines all over the world and has a long history of use in traditional systems of medicine. The primary pungent agents are due to the presence of phenylalkylketones or vanillyl ketones. Gingerol and shogaol are two most active constituents of ginger based preparations. They are reported to demon...