Bis(cyclopropylethynyl)zirconocene shows a bisected conformation in the crystal: the magnitude of the stabilizing conjugation of the Cp2Zr Lewis acid centre with the cyclopropyl substituent across the connecting C[triple bond]C triple bond is assessed by DFT calculations and a comparison with a series of cationic organic and organometallic reference systems.

The frustrated Lewis pair Mes(2)P-CH(2)CH(2)-B(C(6)F(5))(2) reacts with excess 6,6-dimethylpentafulvene to yield a P/B-Lewis pair addition product to an elusive pentafulvene [6 + 4] cycloaddition dimer. This observation may open a new field of utilization of frustrated Lewis pair chemistry.

A bis(imino)acenaphthene (BIAN) ligand containing a pendant Lewis base has been used as a new framework to support a N-heterocyclic phosphenium cation (NHP). Reactivity studies demonstrate the ability of the ligand to act as a Lewis base, while the phosphorus centre provides a Lewis acidic site, giving new opportunities in NHP chemistry.

BACKGROUND The Lewis histo-blood group system consists of 2 major antigens-Lea and Leb-and a sialyl Lewis antigen-carbohydrate antigen (CA) 19-9. We investigated the distribution of Lewis genotypes and evaluated the relationship between the Lewis/Secretor genotypes and the serum level of CA 19-9 in a Korean population to identify whether the serum CA 19-9 levels are influenced by the Lewis/Secr...

The work on development of organic reactions that are tolerant to air and moisture, especially that of carbon-carbon bond forming reactions, had only started in the early 1990s. Our laboratory had approached this subject when it was still in its infancy and had developed methodologies for that end. In this article, our decade of work on indium complexes as Lewis acids is summarised.

Boranes have long been known as the archetypal Lewis acids owing to an empty p-orbital on the boron centre. Meanwhile, Lewis basic tricoordinate boranes have been developed in recent years. Here we report the synthesis of an annulated 1,4,2,5-diazadiborinine derivative featuring boron atoms that exhibit both Lewis acidic and basic properties. Experimental and computational studies confirmed tha...

Current indications (U.S. Department of Education, 2003; Zandberg & Lewis, 2008; Picciano & Seaman, 2009) are that distance learning, in particular online learning, will continue to expand into the foreseeable future. There are some completely online doctoral programs presently operating, but many students continue to flock to the non-traditional executive type leadership cohort-based, on-groun...

BACKGROUND We aimed to compare mediastinoscopy-assisted esophagectomy (MAE) with the Ivor Lewis procedure in T2 middle and lower thoracic esophageal carcinoma patients in fields of perioperative complications and overall survival (OS). METHODS The clinical data of 112 T2 esophageal cancer patients who received MAE (n = 31) or Ivor Lewis procedure (n = 81) from January 2010 to December 2015 we...

OBJECTIVES Tumor-associated macrophages that generally exhibit an alternatively activated (M2) phenotype have been linked to tumor progression and metastasis. However, the role of M2-polarized macrophages in the growth and metastasis of lung adenocarcinoma remains enigmatic. The aim of this study was to explore the effect of M2 macrophages on the proliferation and migration of mouse Lewis lung ...