A novel synthetic route to spirocyclic thiazolidinediones is reported by utilizing ring-closing metathesis (RCM). A selective cross metathesis (CM) of N-allyl azaspiro derivatives with different olefins has been demonstrated to prepare substituted azaspiro-[4.4]nonenediones. The X-ray crystal structure of a spirocyclic thiazolidinedione dimer is described, which has been prepared in two steps f...

A series of general and selective Pd(II)-catalyzed Heck reactions were investigated under mild reaction conditions. The first protocol has been developed employing an imidazole-based secondary phosphine oxide (SPO) ligated palladium complex (6) as a precatalyst. The catalytic coupling of aryl halides and olefins led to the formation of the corresponding coupled products in excellent yields. A v...

With the demand for gasoline and diesel expected to decline in near future, crude-to-chemicals technologies have potential become most important processes petrochemical industry. This trend has triggered intense research maximize production of light olefins aromatics at expense fuels, which calls disruptive able transform crude oil chemicals an efficient environmentally friendly way. Here we pr...

Beside Ziegler-Natta and Phillips catalysts the development of methylaluminoxane (MAO) as cocatalyst in combination with metallocenes or other transition metal complexes for the polymerization of olefins has widely increased the possibilities in controlling the polymer composition, polymer structure, tacticity and special properties with high precision. These catalysts allow the synthesis of is...

The two isomeric 20(22)-olefins and the four isomeric 20,22-epoxides of cholesterol have been examined as possible intermediates in the conversion of cholesterol to pregnenolone both by crude extracts of acetone-dried bovine adrenal cortex mitochondria, and by a partially purified cytochrome P-450 specific for the side chain cleavage ( P 4 5 0 ~ ~ ~ ) . The quantities of pregnenolone (measured ...