Journal:
:reports of biochemistry and molecular biology
0
mohammad reza khakzad tel: +98 9151176352; fax: +98 51- 32250048
farhad salari immunology research center, medical school, mashhad university of medical sciences, mashhad, iran
maryam javanbakht department of psychiatrics, islamic azad university, mashhad branch, mashhad, iran
maryam hojati noor hedayat center of autism spectrum disorders, mashhad, iran
abdolreza varasteh allergy research center, mashhad university of medical sciences, mashhad, iran
mojtaba sankian immunology research center, medical school, mashhad university of medical sciences, mashhad, iran
background: transforming growth factor-β1 (tgf-β1) has been found to play a crucial role in early central nervous system development. several studies have illustrated decreased tgf-β1 levels in sera and brains of autistic children. two point mutations in the tgf-β1 signal peptide at 869t/c and 915g/c have been reported to influence tgf-β1 expression. the aim of the present study was to investig...
