Large unresectable STS presents a therapeutic challenge. Several options are being explored to avoid amputation without compromising the oncological outcome. Neoadjuvant chemotherapy delivers inconsistent and rather unsatisfactory results, preoperative radiotherapy compromises healing, hence it can impede adjuvant systemic treatment. We present case report of neoadjuvant use isolated limb perfu...

Injury to the lower extremity is common in the current conflicts, often severely affecting the foot and ankle. Secondary to continued surgical advances, many lower extremities are able to undergo limb salvage procedures. However, scoring systems still do not reliably predict which patient will be best served with an amputation or limb salvage. Because of this, limb salvage should be attempted w...

The current military conflicts of Operation Enduring Freedom and Operation Iraqi Freedom have been characterized by high-energy explosive wounding patterns, with the majority affecting the extremities. While many injuries have resulted in amputation, surgical advances have allowed the orthopaedic surgeon to pursue limb salvage in the face of injuries once considered unsalvageable. The military ...

The aim of present study was to a) assess the type and the distribution of peripheral arterial disease in diabetic patients presenting to the Endocrine Clinic. b) Plan revascularization and limb salvage of the affected limbs. During the past one year we evaluated and managed eleven patients of type 2 Diabetes and limb-threatening lower extremity ischemia from the moment of diagnosis to revascul...

INTRODUCTION The Authors reports their experience with the use of femoro-femoral cross-over bypass graft in the management of acute lower limb ischaemia. PATIENTS AND METHODS Fourteen femoro-femoral bypass graft were performed for acute lower limb ischaemia due to unilateral thrombosis of iliac and femoral artery in 8 cases, late unilateral occlusion of a branch of previous aortobifemoral byp...

Ewing’s sarcoma (ES) usually affects patients between 10 and 19 years of age has a rapid progression. The main goal surgical treatment is to remove the tumour with at least wide margins, limb salvage being achievable in most cases. In recent years, modular endoprostheses have become one methods used children. From August 2012 May 2019, six histologically diagnosed ES underwent surgery reconstru...

embolectomy has long been the gold standard for treating limbs acutely threatened by arterial occlusion. delayed embolectomy has not been investigated adequately due to the belief that accompanying mortality and morbidity render the case futile. following our previous experience with late arterial repair for leg or knee salvage i we applied the same principle to limbs threatened with prolonged ...

traumatic injuries to the subclavian-axillary artery, although uncommon, are associated with high morbidity and mortality rates if not managed promptly. the emergence of endovascular techniques offers an alternative to the surgical management of these injuries. we herein present 4 cases of traumatic subclavian-axillary artery injury with limb ischemia successfully managed via the endovascular a...

Over a 16-year period, 135 custom-made distal femoral prostheses, based on a fully constrained Stanmore-type knee replacement, were used in the treatment of primary malignant or aggressive benign tumours. Survivorship analysis showed a cumulative success rate of 72% at five years and 64% at seven years. Intact prostheses in 91% of the surviving patients gave good or excellent functional results...

BACKGROUND Isolated limb perfusion (ILP) with tumor necrosis factor (TNF) and melphalan is highly effective in treating limb-threatening soft tissue sarcoma (STS) and other bulky tumors. Because of fear of TNF-associated toxicity, ILP with TNF is not offered to older patients in some cancer centers, although especially in older patients, every attempt to avoid an amputation that may end their i...