Let e and n be positive integers and S = {x1, . . . , xn} be a set of n distinct positive integers. The n × n matrix having eth power [xi, xj ] of the least common multiple of xi and xj as its (i, j)-entry is called the eth power least common multiple (LCM) matrix on S, denoted by ([S]). The set S is said to be gcd closed (respectively, lcm closed) if (xi, xj) ∈ S (respectively, [xi, xj ] ∈ S) ...

ABSTRACT: 10 Owing to the complexity of neurodegenerative diseases, multiple cellular types need to be targeted 11 simultaneously in order for a given therapy to demonstrate any major effectiveness. Ultrasound12 sensitive coated microbubbles (in a targeted nanoemulsion) are available. Versatile small-molecule 13 drug(s) targeting multiple pathways of Alzheimer's disease pathogenesis are known. ...

Let e and n be positive integers and S = {x1, . . . , xn} be a set of n distinct positive integers. The n × n matrix having eth power [xi, xj ] of the least common multiple of xi and xj as its (i, j)-entry is called the eth power least common multiple (LCM) matrix on S, denoted by ([S]). The set S is said to be gcd closed (respectively, lcm closed) if (xi, xj) ∈ S (respectively, [xi, xj ] ∈ S) ...

The sum rate maximization in multiuser MIMO broadcast channels is investigated in this paper. We first propose an approach under a total power constraint. Compared with the most related methods in the literature, the proposed method can be easily adapted to a more realistic per-antenna power constraint. Since the power of each antenna is limited individually by the linearity of its power amplif...

Constraint hierarchies have been proposed to overcome over-constrained systems of constraints by specifying constraints with hierarchical preferences. They are widely used in HCLP (Hierarchical Constraint Logic Programming), CIP (Constraint Imperative Programming) and graphical user interfaces. The advantages of constraint hierarchies are a declarative expression of preferred constraints and th...

Obtaining protein profiles from a homogeneous cell population in tissues can significantly improve our capability in protein biomarker discovery. In this study, unique protein profiles from the top and bottom sections of mouse crypts and Apc(Min+/-) adenomas were obtained using laser capture microdissection (LCM) combined with MALDI MS. Statistically significant protein peaks with differential ...

s t lcm lcm*2 lcm*4 gcd gcd/2 gcd/4 s t lcm lcm*2 lcm*4 gcd gcd/2 gcd/4 Table 1: Execution times (ms) for cyclic(s) to cyclic(t) redistribution on 32 processors. other block sizes t. Fig. 3 shows the total times in milliseconds for a cyclic(192) to cyclic(8) redistribution on 32 processors for increasing data sizes. This redistribution corresponds to the cyclic(Y t) to cyclic(t) case with Y = 2...

Laser capture microdissection (LCM) has become an important tool in biological research, permitting isolation of specific cell populations from frozen tissue samples containing a mixture of cell types. Cells obtained by LCM can be directly analyzed by matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS). We report here methodology for the preparation and analysis of LCM capt...

INTRODUCTION Studies on the association of a polymorphism in codon 72 of the p53 tumour suppressor gene (rs1042522) with cervical neoplasia have inconsistent results. While several methods for genotyping p53 exist, they vary in accuracy and are often discrepant. METHODS We used latent class models (LCM) to examine the accuracy of six methods for p53 determination, all conducted by the same la...