Over the last decade the use of generalized linear models (GLMs) in modelling actuarial data received a lot of attention, starting from the actuarial illustrations in the standard text by McCullagh & Nelder (1989). Standard GLMs however model a sample of independent random variables. Since actuaries very often have repeated measurements or longitudinal data (i.e. repeated measurements over time...

BACKGROUND Sarcopenia is associated with adverse outcomes such as physical disability, poorer quality of life, and death. Helicobacter pylori (HP) eradication increases ghrelin secretion, which may be a possible treatment for sarcopenia. We investigated whether HP eradication reduces the risk of low muscle mass (LMM), which is an integral component of sarcopenia. MATERIALS AND METHODS Healthy...

Intratracheal administration of low molecular mass (LMM) hyaluronan (200 kDa) results in greater neutrophil infiltration in the lungs of TLR4(-/-) mice compared with that in wild-type mice. In general, enhanced neutrophil infiltration in tissue is due to cell influx; however, neutrophil apoptosis also plays an important role. We have assessed the effects of TLR4 in the regulation of neutrophil ...

Most of the approaches to solve the unmixing problem are based on the Linear Mixing Model (LMM) which is questionable. Therefore, nonlinear spectral model is generally used to study the effects of multiple scattering in the complex surfaces. In this paper, we have demonstrated the application of Radiative Transform Equation (RTE) based Hapke multi scattering model. The Hapke model based non-lin...

Using forest inventory data and Landsat ETM+ data, linear fixed-effects models and linear mixed-effects models are developed based on the allometric growth model. The surface area of the normalized difference vegetation index (NDVIsa) is developed from the triangulated irregular network (TIN) with the aid of image-processing and the three-dimensional analysis extensions of Environmental Systems...

BACKGROUND Our objective was to determine what effect maternal BMI has on fetal growth rate in the early first trimester. METHODS This was a prospective observational study of singleton pregnancies with certain dates, initially presenting for a transvaginal scan (TVS) before 12 weeks of gestation. Maternal characteristics (BMI, ethnicity, maternal age, obstetric history, abdominal pain and va...

Linear Mixed models (LMMs) that incorporate genetic and spatial covariance structures have been used for many years to estimate genetic parameters and to predict breeding values in animal and plant breeding. Although the theoretical aspects for extending LMM to generalised linear mixed models (GLMMs) have been around for some time, suitable software has been developed only within the last decad...

The enhancement of small vessels in MRA imaging is an important problem. In this paper, we propose using local maximum mean (LMM) processing to enhance the detectability of small vessels. At each voxel in the original three-dimensional (3-D) data set, the LMM over the line segments in the cube centered at the voxel is taken and used to form the 3-D LMM data set. The maximum intensity projection...