Diabetes is a risk factor for Alzheimer disease (AD). Apolipoprotein E (ApoE) and several genes related to AD have recently been identified by genome-wide association studies (GWAS) as being closely linked to lipid metabolism. Lipid metabolism and glucose-energy metabolism are closely related. Here, we review the emerging evidence regarding the roles of lipid and glucose metabolism in the modul...

Background: Recent studies have shown that chemotherapy can cause abnormal glucose and lipid metabolism in breast cancer patients; however, the effects of different regimens on profiles this population remain unclear.

Lipid mediators are a class of signaling molecules that play important roles in various physiological processes, including inflammation, blood pressure regulation, and energy metabolism. Exercise has been shown to affect the production metabolism several types lipid mediators, prostaglandins, leukotrienes, sphingolipids, platelet-activating factors endocannabinoids. Eicosanoids, which include p...

Reactive oxygen species (ROS)plays an important role in sperm motility. The physiological generation at low concentration induces beneficial effects on sperm functions and plays a significant role in sperm metabolism. Meanwhile, the excessive generation of reactive oxygen species can overwhelm protective mechanism and triggers changes in lipid and protein layers of sperm plasma membrane, which ...

Berberine (BBR) has been shown to exhibit protective effects against diabetes and dyslipidemia. Previous studies have indicated that BBR modulates lipid metabolism and inhibits hepatic gluconeogensis by decreasing expression of Hepatocyte Nuclear Factor-4α (HNF-4α). However, the mechanism involved in this process was unknown. In the current study, we examined the mechanism of how BBR attenuates...

Mol. Nutr. Food Res. 2021, 65, 202100516 DOI: 10.1002/mnfr.202100516 Dietary phytosterols and sterol oxidation products exhibit significant different effects on atherosclerosis, changes in liver lipid metabolism may provide another insight for their effects. As revealed by lipidomes proteome this report, besides cholesterol, also greatly affected glycerophospholipids & glycerolipids sphingolipi...

Copper is an essential trace element that acts as a cofactor in various enzyme active sites the human body. It participates numerous life activities, including lipid metabolism, energy and neurotransmitter synthesis. The proposal of “Cuproptosis” has made copper metabolism-related pathways research hotspot field tumor therapy, which attracted great attention. This review discusses biological pr...

To systematically investigate the effects of different protein/energy (P/E) ratio diets on microstructure and metabolic response black sea bream liver, fish (initial weight 11.20 ± 0.20 g) were fed three isoenergetic (20.9 kJ/g) with varying protein/lipid levels (LR, 28.8% protein/26.3% lipid; MR, 37.5%...