We here demonstrate a new route for deposition of phosphorous based materials by atomic layer (ALD) using the phosphites Me3PO3 or Et3PO3 as precursors. These contain in oxidation state (III) and are open reduced phases ALD. have investigated their applicability synthesis LiPO AlPO characterized growth means situ quartz crystal microbalance. Phosphites good alternatives to established phosphate...

The related lipo(depsi)peptide antibiotics daptomycin and friulimicin B show great potential in the treatment of multiply resistant gram-positive pathogens. Applying genome-wide in-depth expression profiling, we compared the respective stress responses of Bacillus subtilis. Both antibiotics target envelope integrity, based on the strong induction of extracytoplasmic function sigma factor-depend...

Methyl glycyrrhetinate was esterified at position C3 of ring A using different amino acids. A short, unbranched chain of four carbon atoms with two amino groups in positions 2 and 4 was shown to be the most active compound of this series (IC50 = 0.8 M on liposarcoma Lipo cells). These compounds trigger apoptosis as shown by an acridine orange/ethidium bromide assay, trypan blue tests and DNAlad...

Submit Manuscript | http://medcraveonline.com Abbreviations: GLPs: Gracilaria Lemaneiformis Polysaccharides; FTIR: Fourier Transform Infrared Spectroscopy; GC: Gas Chromatography; HPGPC: High Performance Gel Permeation Chromatography; NK: Natural Killer; IL-2: Interleukin-2; IFN-γ: Interferon-γ; TNF-α: Tumor Necrosis Factor-α; BRM: Biological Response Modifier; ConA: Concanavalin A; LPS: Lipo P...

The pregnant patient with partial lipodystrophy developing acute renal failure—onset of de novo membranoproliferative glomerulonephritis Key words: acute renal failure; pregnancy; partial lipo-towards the end of the gestation period, between 34 dystrophy; low C3; membranoproliferative nephritis and 38 weeks, and it is invariably the result of pre-eclampsia and its complications or the result of...

Many immunostimulatory drugs, such as agonistic antibodies to CD137 and interleukin (IL)-2, generate effective antitumor immune responses in preclinical studies, but demonstrate serious toxicity profiles after systemic administration, which hampers their clinical application. We recently discovered that a combination of antiCD137 with an extended half-life IL-2-Fc fusion protein (lacking Fc rec...

We frequently study processes that alter microvascular permeability in the heart. Myocardial microvascular permeability has been estimated by determining the filtration independent reflection coefficient for beta-lipoprotein (sigma beta-LIPO). This technique requires the measurement of myocardial lymph flow rate and the lymph-to-plasma protein concentration ratio. Unfortunately, it is a nonsurv...