Important immune-mediated liver illnesses include autoimmunity hepatitis (AIH) and primary biliary cirrhosis. Typically, they are distinguished based on histological, biochemical, serological, clinical parameters. Diagnostic criteria for many conditions typically met by patients with autoimmune disease. The diagnosis of AIH/primary sclerosing cholangitis overlap is a mix biochemistry, autoantib...

Background and Aim: Non-invasive tests (NITs) are important tools for ruling-out advanced fibrosis in NAFLD. However, many patients still require liver-biopsy due to the comparatively poor positive predictive value (PPV) substantial grey-zone associated with NITs. AGILE-3+ score is a novel NIT which includes liver stiffness measurement (LSM) on transient elastography commonly measured clinical ...

at first, in order to define acute toxicity of diazinon insecticide and butachlor herbicide, acute toxicity tests (lc5096h) were done, based on standard method (1989) o.e.c.d. in static way and for 96 hours. and the amount of acute toxicity (lc5096h) of diazinon and butachlor in 1 to 2 gram vimba vimba persa fry larva was determined to be 0.09 and 0.61 respectively. in order to do histology stu...

background and purpose: problem-based learning (pbl) is a term used within education for a range of teaching approaches that encourage students to learn through the structured exploration of a problem. histology comes early in the curriculum and the medical students seem unable to see the value of the content, they don't appear to be motivated to learn the content. this project used pbl to help...

BACKGROUND & AIMS Liver biopsy (LB) is performed if non-invasive work-up of liver disease is inconclusive. The examination of liver tissue occasionally reveals normal histology. Long-term follow-up of such patients has not been performed. METHODS We identified a total 70 subjects from our LB database with elevated liver tests and normal liver histology after a mean of 90.5 ± 52.3 (range 15-21...

AIM To evaluate changes in liver histology in patients with human immunodeficiency virus/hepatitis C virus coinfection non-responders to a suboptimal Interferon+Ribavirine regimen. MATERIALS AND METHODS We investigated 49 patients with two sequential liver biopsies: 18 were non-responders to Interferon+Ribavirine treatment (Group hepatitis C virus Rx) administered after the 1st liver biopsy w...

Objectives: Carbon tetrachloride (CCl4) is one of the most dangerous hepatotoxic environmental pollutants thus this study aimed at investigating the potential preventive effect and mechanism of crocin against CCl4induced hepatotoxicity. Methods: Forty Male rats were allocated for two weeks treatment with; corn oil, CCl4 in corn oil, crocin (100 mg/ kg), or crocin plus CCl4. At time of euthanasi...