Primary small cell carcinoma of the liver is very rare tumor. Till date only 12 cases have been reported in the English literature. We are reporting a case of primary small cell carcinoma of the liver in a female patient. She had 13 cm x 7 cm tumor in the right lobe of liver and fine needle aspiration cytology revealed features of small cell carcinoma. After ruling primary from elsewhere, patie...

lead is one of the heavy metal that is very toxic for environment and organisms. lead can inhibits many physiological processes and it is so dangerous for body tissues. in this study, four groups of fish (carassius auratus) 35 in each, were used for experiment. group 1 was as control, in group 2 fishes were exposed to lead acetate at concentration of 8. 5 mg/l, fishes in group 3 and 4 were also...

background: autoimmune hepatitis (aih) in childhood has variable modes of presentation, and the disease should be suspected and excluded in all children presenting with symptoms and signs of prolonged or severe acute liver disease. in aih, the liver biopsy histopathology shows inflammation in addition to presence of serum autoimmune antibodies and increased levels of immunoglobulin g (igg). obj...

Previous studies have demonstrated that acute exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) by injection leads to inhibition of caudal fin regeneration in zebrafish. Since the TCDD exposure in these studies is systemic, it is possible that pathology in organs other than the fin could result in inhibition of fin regeneration. Therefore, histopathology of adult zebrafish (Danio rerio) or...

BACKGROUND Aleutian mink disease virus (AMDV) is found world-wide and has a major impact on mink health and welfare by decreasing reproduction and fur quality. In the majority of mink, the infection is subclinical and the diagnosis must be confirmed by serology or polymerase chain reaction (PCR). Increased knowledge based on a systematically description of clinical signs, pathology and histopat...

BACKGROUND Fulminant hepatitis progresses to acute liver failure (ALF) when the extent of hepatocyte death exceeds the liver's regenerative capacity. Although small interfering RNA (siRNA) appears promising in animal models of hepatitis, the approach is limited by drawbacks associated with systemic administration of siRNA. The aim of this study is to develop a hepatocyte-specific delivery syste...

Macrophage migration inhibitory factory (MIF) regulates macrophage accumulation at sites of injury and can promote the inflammatory response. We studied MIF expression in the intragastric feeding rat model for alcoholic liver injury. Male and age-matched female rats were fed ethanol or dextrose with fish oil. Two groups of male rats were fed medium-chain triglycerides with ethanol or dextrose. ...

objective(s):typhoid fever is a dreadful disease of a major threat to public health in developing countries. vaccination with bacterial immunodominant components such as surface proteins may prove as a potent alternative to live attenuated vaccines. invh, an important part of needle complex in type three secretion system (ttss) plays important role in efficient bacterial adherence and entry int...

L IVER allograft rejection is diagnosed largely base.d on liver function tests indicating graft damage associated with rejection. but histopathological diagnosis using biopsy is still necessarv. Since it can be difficult to distinguish rejection from ~ther causes of graft damage in the absence of liver histopathology. detection of a marker for immune activation and a mediator of inflammation co...

Drug-induced hepatotoxicity most commonly manifests as an acute hepatitis syndrome and remains the leading cause of drug-induced death/mortality and the primary reason for withdrawal of drugs from the pharmaceutical market. We report a case of acute liver injury in a 12-year-old Hispanic boy, who received a series of five antibiotics (amoxicillin, ceftriaxone, vancomycin, ampicillin/sulbactam, ...