Rat liver, liver homogenates, and microsome fractions separated therefrom were examined systematically in the electron microscope in sections of OsO(4)-fixed, methacrylate-embedded tissue and pellets. It was found that most microsomes are morphologically identical with the rough surfaced elements of the endoplasmic reticula of hepatic cells. They appear as isolated, membrane-bound vesicles, tub...

introduction: the impact of chromium exposure was studied on liver, kidney, testis, spleen, cerebrum and cerebellum of male wistar rats (80-100 g body weight). material & method: it was observed that treatments of rats with chromium (i.p. at a dose of 0.8 mg / 100 g body weight per day) for a period of 28 days caused significant increase in chromium content while declining the body weight along...

The heavy metals concentrations including Zinc, Copper, Lead and Cadmium (Zn, Cu, Pb and Cd) in water and sediments in Gorgan Bay and their accumulation in Rutilus frisii kutum, Acipenser persicus, Rutilus rutilus caspicus and Cyprinus carpio organs (gills, muscle, kidney and liver) were investigated. There was substantial increase in concentration of heavy m...

The heavy metals concentrations including Zinc, Copper, Lead and Cadmium (Zn, Cu, Pb and Cd) in water and sediments in Gorgan Bay and their accumulation in Rutilus frisii kutum, Acipenser persicus, Rutilus rutilus caspicus and Cyprinus carpio organs (gills, muscle, kidney and liver) were investigated. There was substantial increase in concentration of heavy m...

Background: This study evaluated the effects of 1:1 mixture of aqueous root bark extracts of Anogeissus leiocarpus (DC) Guill & Perr (Combretaceae) and Terminalia avicennioides Guill & Perr (Combretaceae) in male rats. Methods: Male rats were orally administered a 1:1 mixture of both extracts (250, 500 and 1000 mg/kg body weight) for seven days. Liver and kidney function indices, haematologica...

Mycograb (NeuTec Pharma plc) is a human genetically recombinant antibody against fungal heat shock protein 90 (HSP90). Antibody to HSP90 is closely associated with recovery in patients with invasive candidiasis who are receiving amphotericin B (AMB). Using in vitro assays developed for efficacy assessment of chemotherapeutic antifungal drugs, Mycograb showed activity against a wide range of yea...

ObjectivesPrevious reports on association of autoantibodies with histological severity in nonalcoholic fatty liver disease (NAFLD) have revealed inconsistent results. Therefore, this study was undertaken to find the impact NAFLD.MethodsAll cases diagnosis NAFLD during January 2016 2021 were included study. Laboratory parameters recorded, and assessment done. The positivity autoimmune markers de...

Introduction: The impact of chromium exposure was studied on liver, kidney, testis, spleen, cerebrum and cerebellum of male Wistar rats (80-100 g body weight). Material & Method: It was observed that treatments of rats with chromium (i.p. at a dose of 0.8 mg / 100 g body weight per day) for a period of 28 days caused significant increase in chromium content while declining the body weight a...

Anti-mitochondrial antibody (AMA) is a highly specific and sensitive test for primary biliary cirrhosis (PBC). It can also be detected as positive in connective tissue diseases, such as scleroderma, CREST, systemic lupus erythematosus, and Sjögren’s syndrome (1). In general, HEp-2 cells are analyzed with immunofluorescence microscopic and/or extractable nuclear antigen (ENA) tests in rat liver ...

BACKGROUND Liver enzymes elevations (LEE) can be observed after kidney transplantation due to multifactorial causes. OBJECTIVES We performed a retrospective study on 1589 kidney transplants, 971 male and 618 female, who were hepatitis B surface antigen (HBsAg) and hepatitis C virus-antibody (HCV Ab) negative, and had no other liver diseases, to detect the prevalence of LEE and its risk factor...