de Groot et al. [1] reported that an increased fall risk from the use of psychotropic drugs was associated with impairments in postural control, which these drugs could induce [1]. The effects seem to be more pronounced when the half-life is longer [1]. Hangover effects on postural control (after 8 h of administration) were found mainly for benzodiazepines with an intermittent or long half-life...

Co-administration of a long-acting β2-agonist and a long acting muscarinic antagonist produces superior bronchodilation compared with their individual effects. Our preclinical data indicated that combining aclidinium bromide (ACLI) and formoterol fumarate (FORM) provides synergistic benefit on smooth muscle relaxation of both large and small human airways. Data from more than 2,000 patients in ...