The present work aimed to investigate the occurrence of 24 drugs and endocrine disruptors in filters washing water from Bolonha Water Treatment Plant Belém, State Pará, Brazil, since these residues are often released into courses. correlation microcontaminants with physicochemical biological characteristics investigated studied matrix was also evaluated. For research, six sampling campaigns wer...

Treatment during pregnancy is problematic. The Food and Drug Administration established drug categories to help in the treatment process. First-generation antihistamines are considered safe but they have sedative properties. Second-generation antihistamines cause less adverse reactions but besides cetirizine and loratadine they belong to category C. All retinoids should be avoided during pregna...

BACKGROUND Phenylephrine and pseudoephedrine are sympathomimetic drugs belonging to the phenylamine family. Adverse cutaneous effects associated with these drugs have been reported but, in view of their frequent use, appear to be rare. The very close chemical structures of these drugs could explain potential cross-reactions among them but the results reported in the literature are controversial...

Cyclodextrins (CDs) have been considerably raised interest and attention in the pharmaceutical sciences due to their specific ability to form inclusion complexes with many drugs, leading to significant enhancements of the solubility, stability and bioavailability, as well as decrease in the bitterness and tissue irritation of the drugs (Carrier et al., 2007; Challa et al., 2005; Miller et al., ...