نتایج جستجو برای: low dose interferon
تعداد نتایج: 1503914 فیلتر نتایج به سال:
The effects of chronic low-dose radiation on human health have not been well established. Recent studies have revealed that neural progenitor cells are present not only in the fetal brain but also in the adult brain. Since immature cells are generally more radiosensitive, here we investigated the effects of chronic low-dose radiation on cultured human neural progenitor cells (hNPCs) derived fro...
background: interferons (ifns) are common therapeutics for several diseases such as viral hepatitis, multiple sclerosis and malignancy. a variety of autoimmune related side effects have been observed during ifn therapy. rare cases of myopathy, polymyositis or dermatomyositis have been reported during therapy with high doses of ifn^5. case presentation: in this report, we describe a case with se...
Pretreatment of chicken embryo cells with homologous but not heterologous interferon inhibits the synthesis of vaccinia virus early messenger ribonucleic acid (mRNA). This inhibition is seen in the presence of cycloheximide, i.e., in the absence of protein synthesis, suggesting that the virion-bound transcriptase may be the target of the antiviral activity associated with interferon treatment. ...
Stephen Richardson, MD; Jeanne B. Budgin, DVM; Jacqueline M. Junkins-Hopkins, MD; Carmela C. Vittorio, MD; Jason Lee, MD; Wallace T. Miller, Jr, MD; Alain H. Rook, MD; Ellen J. Kim, MD; Departments of Dermatology (Drs Richardson, Junkins-Hopkins, Vittorio, Rook, and Kim) and Radiology (Dr Miller), University of Pennsylvania Health System; Department of Dermatology, University of Pennsylvania Sc...
This international, randomized, active-controlled, parallel-group, double-blind dose-finding study compared peginterferon alfa-2b (PegIntron) to interferon alfa-2b for the initial treatment of compensated chronic hepatitis C. We randomly assigned 1,219 subjects to receive either the standard three-times-weekly (TIW) interferon alfa-2b dose (3 MIU) or the once-weekly (QW) peginterferon alfa-2b (...
Background: Pharmacological therapies of proven efficacy in corona virus disease 2019 are still lacking with no antiviral treatment. Impaired type I interferon activity may be responsible for severe COVID-19 patient. We performed prospective, observational, open-label study to evaluate the and safety a single dose Pegylated IFN-α2b addition Remdesivir moderate cases. Aim: The aim this is assess...
To study the effect and mechanism of Baitouweng decoction, mesalamine its combination with an enema in treatment ulcerative proctitis rats is objective study. The were divided into seven groups: Control (Normal), model (ulcerative proctitis), mesalamine, lowdose decoction combined medium-dose high-dose group. Except for control group, all induced a 5 % acetic acid solution proctitis. severity w...
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