A 13-year-old boy with no risk factors for lung cancer presented with a massive left-sided pleural effusion and a mediastinal shift on chest radiography and computed tomography. A chest tube drained bloody pleural fluid with an exudative pattern. A pleural biopsy and wedge biopsy of the left lower lobe revealed mucinous adenocarcinoma in the left lower lobe wedge biopsy and metastatic adenocarc...

Although distinguishing metastatic colorectal adenocarcinoma from primary lung adenocarcinoma is often difficult, pre- or intra-operative identification is very important, as the resection areas for each diagnosis differ substantially. CDX2, a recently cloned homeobox gene, represents a highly specific and sensitive marker of colorectal adenocarcinoma. We evaluated CDX2 expression using pre- an...

OBJECTIVE To determine the impact that open lung biopsy findings have on decisions regarding changes in the treatment strategies employed for critically ill patients presenting diffuse pulmonary infiltrates and suffering from refractory acute respiratory failure, as well as on their clinical improvement. METHODS This study involved 12 mechanically ventilated patients with acute respiratory fa...

Introduction: Cytological evaluation is an important, usually initial diagnostic modality in patients with suspected malignant lung masses. Bronchoscopic washing, bronchoalveolar lavage, bronchial brushing and fine needle aspirations may complement tissue biopsies the diagnosis of cancer. This study was undertaken to compare efficacy wash cytology correlate it histopathology cases cancer at a t...

The sensitivity of all fiberoptic bronchoscopic techniques in case of a peripheral lung cancer is 69%. In the study, it was aimed to assess the contribution of broncoalveolar lavage (BAL) performed before and after standard biopsy procedures in the diagnosis of peripheral lung cancer. The patients with peripheral lung lesion in radiology, and normal bronchoscopic findings were included in the s...

AIMS To investigate the histological evolution in the development of pleuroparenchymal fibroelastosis (PPFE). METHODS AND RESULTS We examined four patients who had undergone surgical lung biopsy twice, or who had undergone surgical lung biopsy and had been autopsied, and in whom the histological diagnosis of the first biopsy was not PPFE, but the diagnosis of the second biopsy or of the autop...

The diagnosis of diffuse pulmonary disease is a problem which frequently concerns chest physicians, and, even after full clinical, radiological, bacteriological, and physiological investigations, the aetiology is often obscure. A lung biopsy with histological examination may be necessary in order to establish the diagnosis. To obtain a lung biopsy, thoracotomy is generally considered to be nece...

conclusions in patients with liver cirrhosis, when there is evidence of severe pulmonary disease without proper response to treatment, the possibility of invasive pulmonary fungal infection should be considered. introduction invasive pulmonary aspergillosis (ipa) is a fatal disease usually occurring in patients with neutropenia resulted from chemotherapy for malignancy. the other risk factors i...