نتایج جستجو برای: lymphocyte globulin
تعداد نتایج: 74281 فیلتر نتایج به سال:
BACKGROUND The therapeutic efficacy of horse antilymphocyte globulins (ALG) or of rabbit antithymocyte globulins (ATG), used for both the prevention and treatment of allograft rejection has been well documented. However, clinical use of these heterologous antibodies can result in the production of antibodies against horse or rabbit proteins and in the development of serum sickness via circulati...
A number of diseases in man are associated with markedly increased gamma globulin levels in the serum and an even greater increase in total gamma globulin pool. The most striking of these is multiple myeloma, but elevations are also seen in cirrhosis of the liver, certain of the collagen diseases such as lupus erythematosus and rheumatoid arthritis, and a variety of chronic infectious processes...
Immunization of guinea pigs with denatured autologous gamma globulin results in the development of delayed hypersensitivity to some form of gamma globulin. When the autologous gamma globulin is subjected to denaturation with alkaline treatment as employed in this study, guinea pigs regularly develop reactivity to the immunizing material and occasionally to some form of heterologous gamma globul...
Both synthetic and catabolic processes determine the serum gamma-globulin level. The rate of gamma-globulin synthesis appears to be the primary factor determining the amount of serum gamma-globulin. Increase of gamma-globulin synthesis (as may occur following immunization or development of plasma cell tumor) elevates the serum gamma-globulin level. This, in turn, accelerates the fractional rate...
The protein of human serum, tentatively designated beta(1C)-globulin, was shown to possess serological activity and to be related to the complement system. Another serum protein (beta(1A)-globulin) was identified as the inactivated form of beta(1C)-globulin. Incubation of fresh serum with various immune precipitates or with soluble gamma-globulin aggregates at 37 degrees C. resulted in the remo...
The serological and physicochemical properties of the following three forms of human anti-gamma-globulin factors were compared: (a) rheumatoid factors; (b) Milgrom type anti-gamma-globulin factors; and (c) factors directed against an antigen in human gammaG-globulin that is hidden in the intact molecule and revealed by enzymatic digestion at low pH. The property common to these factors is abili...
A method has been devised for serological tests with a virus producing rabbit papillomas that become carcinomatous. The discrete character of the growths caused by the virus when suitably diluted fits it notably for quantitative experimentation. It shows no tendency to lie latent in domestic rabbits though it does so on occasion in cottontails, the natural hosts. Sera which partially neutralize...
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