نتایج جستجو برای: lymphoproliferative disorders
تعداد نتایج: 674262 فیلتر نتایج به سال:
This review covers the diagnosis and management of natural killer and peripheral T-cell lymphomas (PTCL). Problems with PTCL include their rarity, representing usually 10-15% of non-Hodgkin's lymphomas in the Western Hemisphere, morphologic heterogeneity, and lack of immunophenotypic markers for clonality. Additionally, their clinical behavior is variable and may not correlate with morphology. ...
Chronic rhinosinusitis (CRS) is one of the most common persistent disorders developed world, requiring input from various specialists including primary care physicians, otolaryngologists, respiratory and allergologists. B-cell lymphoproliferative (BLPDs) are a heterogenous group malignant conditions defined by an accumulation mature B lymphocytes in bone marrow, blood, lymphoid tissues. We pres...
Posttransplantation lymphoproliferative disorders (PTLDs) represent a serious complication of solid organ transplantation. This study assessed the molecular histogenesis of 52 B-cell monoclonal PTLDs, including 12 polymorphic PTLDs (P-PTLDs), 36 diffuse large B-cell lymphomas (DLBCLs), and 4 Burkitt/Burkitt-like lymphomas (BL/BLLs). Somatic hypermutation (SHM) of immunoglobulin variable (IgV) g...
*Correspondence to: Mahmoud Aljurf, Department of Oncology and Laboratory of Tumor Immunology, King Faisal Specialist Hospital & Research Center, MBC 64, PO Box 3354, Riyadh 11211, Saudi Arabia. Tel: +966-1-442-3937; Fax: +966-1-442-3941; E-mail: [email protected] Departments of Oncology and Pathology & Laboratory of Medicine, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Ar...
We have used recombinant human erythropoietin (rHuEPO) in a phase I/II clinical trial to evaluate its ability to reverse refractory anemia in hematologic disorders. rHuEPO was administered subcutaneously 5 days per week at escalating doses (50 to 150 U/kg per day). The aim of treatment was a hemoglobin (Hb) level greater than or equal to 10 g/dL without blood transfusion. Of 25 patients treated...
With improving operative and postoperative survival after pediatric thoracic transplantation, attention has appropriately begun to focus on complications of long-term immunosuppression. One important complication is post-transplantation lymphoproliferative disorders. Much has been learnt about this spectrum of disorders over the last 15 years, including the pivotal role of primary Epstein-Barr ...
Since its discovery in 1994, Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated with lymphoproliferative disorders, particularly in patients infected with human immunodeficiency virus (HIV). The disorders most strongly linked to KSHV are multicentric Castleman's Disease (MCD), primary effusion lymphoma, and diffuse large B-cell lymphomas. We report an unusual case of KSHV-associ...
OBJECTIVES To evaluate CD200 expression in B-cell proliferative disorders. METHODS We analyzed 180 recent specimens of B-cell neoplasms for CD200 expression by flow cytometric immunophenotypic analysis, which is better able to assess relative intensity of staining than immunohistochemical staining. RESULTS We found that hairy cell leukemia exhibits a high level of staining for CD200 in comp...
Introduction: Post-transplant lymphoproliferative disorders (PTLD) are a complication of immunosuppression following organ transplantation. Due to their heterogeneous presentation, diagnosis PTLD can be challenging. Case Report: In this case report, we present patient with metastatic colon cancer, remote history multivisceral transplant 20-years prior, who presented altered mental status and wa...
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