Background Lymphoproliferative disorders (LPDs), including malignant lymphoma, are known to occur in RA patients treated with disease modified antirheumatic drugs (DMARDs). In particular, LPD associated methotrexate (MTX)-treated is often referred as MTX-associated (MTX-LPD). MTX-LPD have various clinical feature and histological findings 1) . We accumulated cases rheumatoid arthritis (MTX-RA-L...

tumefactive fibroinflammatory lesions (tfls) are rare idiopathic benign fibrosclerosing lesions that clinically simulate a malignancy. tfls are seen more frequently in males between 10 and 74 years of age. the usual site of involvement is the head and neck region, but rarely the extremities may be involved. coexisting fibrosclerotic processes have been reported including retroperitoneal fibrosi...

statement of problem: failure of endodontic treatment is determined on the basis of radiographic findings and clinical signs and/ or symptoms of the treated teeth. purpose: the purpose of this study was to determine endodontic treatment failure in relation to various factors influencing it in teeth with periapical lesions (clinically and radiographically). materials and methods: teeth which had...

introduction: chronic sclerosing sialadenitis is a relatively uncommon disorder of the salivary gland. because of its clinical similarity to a salivary gland neoplasm, this condition has been known as kuttner tumor and is classified as a tumorlike lesion. case report: this is the first reported case of bilateral kuttner tumor of the submandibular glands in iran. it was initially diagnosed as a ...

Castleman’s disease (CD) is a rare lymphoproliferative disorder of unknown cause. In even rarer circumstances, it can be associated with POEMS (peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and sk in changes) syndrome. We report a case of multicentric plasma cell CD with POEMS syndrome, who presented with inguinal masses and lower extremity weakness for years. Compu...

POEMS syndrome is a unique clinical entity. Although it's a diagnosis of exclusion, it was previously described by the presence of several typical characteristics as paraproteinemia, polyneuropathy, organomegaly, endocrinopathy, and skin changes. Recently, new criteria were proposed, and the presence of two major and one minor criterion was claimed to suffice for a diagnosis. Both methods consi...

( fi g. 1 ). Cerebrospinal fl uid protein, glucose and cell values were all within the normal ranges. PCR analysis of the cerebrospinal fl uid was positive for JC virus DNA. The diagnosis of PML was established. Because of the advanced state of the hematological malignancy, no empirical treatment was applied. The patient died 6 weeks after the onset of his neurological symptoms. The family deni...