abstract background: recent studies have suggested that oxidative stress (os) may have a contribution in the pathogenesis of endometriosis. however, the results of previous studies regarding os in endometriosis are controversial. the objective of this study was to compare the serum levels of os markers in endometriosis versus the control group. methods: this case-control study was carried out o...

genistein is a soya isoflavone, which is found naturally in legumes, such as soybeans and chickpeas. the intraperitoneal administration of the optimum dose (200 mg/kg) of genistein 24 h and 15 minbefore irradiation (8 gy at a dose rate of 1.02 gy/min) recovered the deficit in protein content (28.63±1.44%) and the dna content (21.61±8.19%) if an average of 5 intervals of autopsies 1st, 3rd, 7th,...

The myocardium is mainly composed of long-lived postmitotic cells with, if there is any at all, a very low rate of replacement through the division and differentiation of stem cells. As a consequence, cardiac myocytes gradually undergo pronounced age-related alterations which, furthermore, occur at a rate that inversely correlates with the longevity of species. Basically, these alterations repr...

glaucoma is the second leading cause of irreversible blindness and a neurodegenerative disease with a complex pathogenesis. increasing evidence suggests that oxidative stress and mitochondrial dysfunction have crucial roles in most neurodegenerative diseases such as glaucoma. the conventional clinical treatment for glaucoma is lowering the intraocular pressure (iop). some patients have normal i...

cirrhosis is associated with hyperdynamic circulation, manifesting as increased cardiac output and decreased systemic vascular resistance. the aim of this study was to investigate the effect of cirrhosis on heart apoptosis and involvement of nitric oxide (no) and oxidative stress in the possible altered apoptosis of cirrhotic hearts. twenty-eight days after bile duct ligation, heart tissues wer...

abstract background: athletes’ recovery is important in improving their performance. nutritional strategies can be effective in enhancing recovery rate. choosing the best food items in appropriate intervals can play effective roles in resynthesis of fuels and recovery of muscle injury. beverage micro and macronutrient content are helpful in fuel restoration. in this study, we assess the effects...

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formalin is widely used in industry and in medicine (as tissue fixative and disinfectant).it contains reactive molecules which have been known for its cytotoxic effects. to evaluate the effect of formalin exposure on the testicular tissue and sperm parameter from neonatal period through physical and sexual maturity, 28 male wister rats were assigned into two equal test and control groups. the t...

background: in this study, the protective effect of thymoquinone (tq) and nigella sativa seeds oil (nso) was evaluated against oxidative damages induced by ethanol in rats. methods: animals were treated with ethanol 40% daily by gavages once a day for 4 weeks. nso and tq were injected intraperitoneal once a day for 4 weeks. the histopathological examination of liver, kidney, brain and heart was...

conclusions the di was found to induce liver damage by oxidative stress mechanisms. silibinin reduced the oxidative stress by inducing antioxidant mechanisms, thereby showing protective effect against di induced liver damage. further studies with silibinin should be performed regarding di toxicity. materials and methods thirty two wistar albino rats were divided into four groups, as follows: 1)...